Purushottam Shrivastava

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We have observed an acute and prolonged lowering of body temperature (hypothermia) following whole body heating (WBH) of mice. This phenomenon of heat-induced hypothermia and the subsequent recovery of normal temperatures have been systematically investigated. The hypothermic period can be characterized by two parameters: Tnadir and a recovery time constant(More)
A muscle-stimulating material made of polyacrylamide gel (PAG) for testing various kinds of hyperthermia applicators was investigated. The permittivity and conductivity dispersion of PAG, as well as an internal wavelength and penetration depth, were in good agreement with those of actual muscle at frequencies between 500 MHz and 3 GHz. A single formula for(More)
PURPOSE To investigate the feasibility, toxicity, and pharmacokinetics of intraperitoneal (i.p.) carboplatin (CB) with concomitant abdomino-pelvic hyperthermia (HT) in advanced ovarian cancer patients. METHODS AND MATERIALS Patients with residual disease mainly confined to the peritoneal cavity after platinum based chemotherapy received an initial course(More)
Distribution of radiation exposure circumcranially for patients undergoing brain scanning with EMI computed tomographic equipment was measured using thermoluminescent dosimeters. The exposures are found to lie in the range of 1-5 R depending on position relative to tube motion. The maximum exposure of 5 R in CT scanning lies between the estimated exposure(More)
These Hyperthermia Quality Assurance guidelines are a result of a joint workshop of the Hyperthermia Committee of the American College of Radiology and the Hyperthermia Physics Center, which is the national quality assurance program under Contract No. N01-CM-37512 with the National Cancer Institute. Hyperthermia technology presently lacks the kind of(More)
The Hyperthermia Physics Center (HPC), under contract with the National Cancer Institute (NCI), has conducted review-type quality assurance (QA) measurements at the five Hyperthermia Equipment Evaluation Centers involved in evaluating the clinical efficacy of a variety of devices for delivering heat treatments to deep-seated human tumours. A summary of the(More)