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Tau Reduction Prevents Aβ-Induced Defects in Axonal Transport
A mechanism for the protective effects of tau reduction in mouse models of Alzheimer’s disease. Amyloid-β (Aβ) peptides, derived from the amyloid precursor protein, and the microtubule-associatedExpand
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Salivary glands harbor more diverse microbial communities than gut in Anopheles culicifacies
BackgroundIn recent years, it has been well documented that gut flora not only influence mosquito physiology, but also significantly alter vector competency. Although, salivary gland and gutExpand
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A unique immuno-stimulant steroidal sapogenin acid from the roots of Asparagus racemosus
A new steroidal sapogenin molecule 1 having unique characteristics, 21-nor and unusual C19 carboxylic acid has been isolated from the roots of Asparagus racemosus. On the basis of chemical evidence,Expand
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Unraveling dual feeding associated molecular complexity of salivary glands in the mosquito Anopheles culicifacies
ABSTRACT Mosquito salivary glands are well known to facilitate meal acquisition, however the fundamental question on how adult female salivary gland manages molecular responses during sugar versusExpand
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Automated measurement of Drosophila jump reflex habituation and its use for mutant screening
In habituation the probability of a behavioral response decreases with repeated presentations of a stimulus. This is a simple kind of learning since it involves an adaptive change in behavior due toExpand
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Hemocytome: deep sequencing analysis of mosquito blood cells in Indian malarial vector Anopheles stephensi.
Hemocytes are tiny circulating blood cells of insects known to play multiple roles in physiological as well as cellular immune responses. However, the molecular nature of hemocytes in blood feedingExpand
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Interorgan Molecular Communication Strategies of “Local” and “Systemic” Innate Immune Responses in Mosquito Anopheles stephensi
Mosquitoes that transmit many deadly infectious diseases also need to keep fighting against many microbial infections. Constitutive expression of multiple antimicrobial peptides (AMPs) in almost allExpand
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Structural and functional prediction analysis of mosquito Ninjurin protein: Implication in the innate immune responses in Anopheles stephensi
Ninjurin, identified as a two-pass transmembrane protein is induced upon nerve injury in vertebrates. Recent studies demonstrate that ninjurins are cell adhesion molecules, capable of regulating manyExpand
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A Synergistic Transcriptional Regulation of Olfactory Genes Drives Blood-Feeding Associated Complex Behavioral Responses in the Mosquito Anopheles culicifacies
Decoding the molecular basis of host seeking and blood feeding behavioral evolution/adaptation in the adult female mosquitoes may provide an opportunity to design new molecular strategy to disruptExpand
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Altered gut microbiota and immunity defines Plasmodium vivax survival in Anopheles stephensi
Blood feeding-enriched gut-microbiota boosts mosquitoes’ anti-Plasmodium immunity. Here, we ask how Plasmodium vivax alters microbiota, anti-Plasmodial immunity and impact tripartiteExpand
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