Puja R Mehta

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Despite their name, resting state networks (RSNs) provide a clear indication that the human brain may be hard-working. Unlike the cardiac and respiratory systems, which greatly reduce their rate of function during periods of inactivity, the human brain may have additional responsibilities during rest. One particularly intriguing function performed by the(More)
Thromboembolism is not uncommon in multiple myeloma (MM) patients on treatment, but its pathogenesis remains poorly understood. We report the results of a prospective randomized trial of 62 newly diagnosed MM patients tested at baseline for hypercoagulability and treated with intensive chemotherapy with or without thalidomide in a randomized fashion. During(More)
We sought kinase domain (KD) mutations at the start of treatment with dasatinib in 46 chronic myeloid leukemia (CML) patients resistant to or intolerant of imatinib. We identified BCR-ABL mutant subclones in 12 (26%) cases and used pyrosequencing to estimate subsequent changes in their relative size after starting dasatinib. Four patients lost their(More)
(marketed as Omniscan, OptiMARK, Magnevist, ProHance, and MultiHance). Rockville, MD: U.S. Food and Drug Administration, June 2006, December 2006, February 2007, May2007. http://www.fda.gov/cder/ drug/advisory/gadolinium_agents.htm (9 January 2009, date last accessed). 10 European Agency for the Evaluation of Medicinal Products (EMEA). Gadolinium-containing(More)
Dobutamine stress echocardiography (DSE) has been proposed as a tool for risk stratification of patients with acute chest pain (ACP). In this single-center study, we evaluated the negative predictive value of DSE in 178 patients who presented with low-risk ACP (normal or inconclusive electrocardiogram and negative markers of myocardial damage) and were(More)
Behçet’s syndrome (BS) is a rare, heterogeneous multisystem inflammatory condition, characterized by recurrent orogenital ulcers and uveitis. Vascular involvement affects 10–30% of patients, is most frequently observed in young males and usually presents as superficial or deep venous thrombosis (DVT) [1]. The spectrum of thrombosis also includes vena cava(More)
Arterial elasticity is decreased in diabetes, but it is unclear whether there is a relationship between glycosylated hemoglobin (HbA1c) and arterial elasticity. To evaluate this question, 111 subjects with diabetes mellitus had HbA1c and arterial elasticity determined in an academic outpatient setting. Three measurements of arterial elasticity indices were(More)
Trichobezoars are intraluminal accretions of ingested hair. The Rapunzel syndrome is a rare form of gastric trichobezoar, with extension into the small bowel, and may be complicated by obstruction, perforation or peritonitis. The majority of reported cases are from Asian countries. We describe the second case from England who, like the earlier report, is(More)