Pui Hang Tam

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MosA is a gene product encoded on a pSym megaplasmid of Sinorhizobium meliloti L5-30. The gene is part of an operon reported to be essential for the synthesis of the rhizopine 3-O-methyl-scyllo-inosamine. MosA has been assigned the function of an O-methyltransferase. However, the reported sequence of this protein is very much like that of(More)
“The author(s), and in the case of a Work Made For Hire, as defined in the U.S. Copyright Act, 17 U.S.C. §101, the employer named [below], shall have the following rights (the “Author Rights”): [...] 3. The right to use all or part of the Article, including the APS-prepared version without revision or modification, on the author(s)’ web home page or(More)
Aims. Recent theoretical predictions of the lowest very high energy (VHE) luminosity of SN 1006 are only a factor 5 below the previously published H.E.S.S. upper limit, thus motivating further in-depth observations of this source. Methods. Deep observations at VHE energies (above 100 GeV) were carried out with the High Energy Stereoscopic System (H.E.S.S.)(More)
Inositol dehydrogenase (EC from Bacillus subtilis is shown to have a nonpolar cavity adjacent to the active site, allowing racemic protected inositol derivatives such as 4-O-benzyl-myo-inositol to be recognized with very high apparent stereoselectivity.
MosA is an enzyme from Sinorhizobium meliloti L5-30, a beneficial soil bacterium that forms a symbiotic relationship with leguminous plants. MosA was proposed to catalyze the conversion of scyllo-inosamine to 3-O-methyl-scyllo-inosamine (compounds known as rhizopines), despite the MosA sequence showing a strong resemblance to dihydrodipicolinate synthase(More)
The synchrotron self-Compton (SSC) emission from Gamma-ray Burst (GRB) forward shock can extend to the very-high-energy (VHE; Eγ >100 GeV) range. Such high energy photons are rare and are attenuated by the cosmic infrared background before reaching us. In this work, we discuss the prospect to detect these VHE photons using the current ground-based Cherenkov(More)
Mycobacterial lipoarabinomannan (LAM) is an important, immunologically active glycan found in the cell wall of mycobacteria, including the human pathogen Mycobacterium tuberculosis. At the core of LAM is a mannan domain comprised of alpha-(1-->6)-linked-mannopyranose (Manp) residues. Previously, we and others have demonstrated that(More)
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