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Femoral nerve blocks for acute postoperative pain after knee replacement surgery.
BACKGROUND Total knee replacement (TKR) is a common and often painful operation. Femoral nerve block (FNB) is frequently used for postoperative analgesia. OBJECTIVES To evaluate the benefits andExpand
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Early versus late initiation of epidural analgesia for labour.
BACKGROUND Pain during childbirth is arguably the most severe pain some women may experience in their lifetime. Epidural analgesia is an effective form of pain relief during labour. Many women haveExpand
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A randomised controlled trial evaluating the impact of targeted vitamin D supplementation on endothelial function in type 2 diabetes mellitus: The DIMENSION trial
We sought to determine if vitamin D supplementation, to target 25(OH)D concentrations of 30–40 ng/mL, improves endothelial function in Singapore’s multi-ethnic type 2 diabetes mellitus population. WeExpand
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Uncontrolled diabetes mellitus: prevalence and risk factors among people with type 2 diabetes mellitus in an Urban District of Karachi, Pakistan.
AIMS This study aimed to explore the prevalence of, and factors associated with, uncontrolled diabetes mellitus (UDM) in a community setting in Pakistan. METHODOLOGY A single-center,Expand
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Association between white matter hyperintensity and medial temporal atrophy at various stages of Alzheimer's disease
Whilst there is evidence implicating small vessel cerebrovascular disease in the pathogenesis of Alzheimer's disease (AD), its specific contribution to the pathophysiology of AD remains unclear. TheExpand
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Cognitive Impairment after Mild Stroke: Development and Validation of the SIGNAL2 Risk Score.
BACKGROUND Post stroke cognitive impairment (PSCI), an important complication of strokes, has numerous risk factors. A scale adequately classifying risk of cognitive impairment 3-6 months after mildExpand
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Investigating analgesic and psychological factors associated with risk of postpartum depression development: a case–control study
Aim The aim of this study was to investigate the role of peripartum analgesic and psychological factors that may be related to postpartum depression (PPD). Methods This case–control study wasExpand
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Automated mandatory bolus versus basal infusion for maintenance of epidural analgesia in labour
Background Childbirth may cause the most severe pain some women experience in their lifetime. Epidural analgesia is an effective form of pain relief during labour and is considered to be theExpand
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Using a Poisson approximation to predict the isotopic distribution of sulphur-containing peptides in a peptide-centric proteomic approach.
Breen et al. (Electrophoresis 2000; 21: 2243) proposed a method for finding monoisotopic peptide peaks in mass spectra based on an approximation of the distribution of different isotopic variants ofExpand
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Early detection of dementia in multilingual populations: Visual Cognitive Assessment Test (VCAT)
Background Early diagnosis of cognitive impairment allows timely intervention with pharmacological and non-pharmacological measures. However, current cognitive evaluation tools do not cater forExpand
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