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-This paper addresses the problem of evaluation of alternative control configurations on the basis of structural characteristics of the process. Relative order is proposed as the main analysis toolâ€¦ (More)

This paper introduces a methodology for the synthesis of nonlinear finite-dimensional output feedback controllers for systems of quasi-linear parabolic partial Å½ . differential equations PDEs , forâ€¦ (More)

- Navneet Kapoor, Andrew R. Teel, Prodromos Daoutidis
- Automatica
- 1998

This paper concerns general MlMO nonlinear processes, whose dynamic behavior is described by a standard state-space model of arbitrary order, including measurable disturbances. The concept ofâ€¦ (More)

- Subbarao Varigonda, Tryphon T. Georgiou, Ronald A. Siegel, Prodromos Daoutidis
- Computers & Chemical Engineering
- 2008

Administration of certain drugs at a steady rate results in deterioration of drug effect, also known as drug tolerance. Periodic delivery is an attractive option for minimizing tolerance andâ€¦ (More)

- Vassilios Sotiropoulos, Marie-Nathalie Contou-Carrere, Prodromos Daoutidis, Yiannis N. Kaznessis
- IEEE/ACM Transactions on Computational Biologyâ€¦
- 2009

Two very important characteristics of biological reaction networks need to be considered carefully when modeling these systems. First, models must account for the inherent probabilistic nature ofâ€¦ (More)

- Ziomara P. Gerdtzen, Prodromos Daoutidis, Wei-Shou Hu
- Metabolic engineering
- 2004

Kinetic models of metabolic networks are essential for predicting and optimizing the transient behavior of cells in culture. However, such models are inherently high dimensional and stiff due to theâ€¦ (More)

-This work concerns systems of quasi-linear first-order hyperbolic partial differential equations (PDEs) with uncertain variables and unmodeled dynamics. For systems with uncertain variables, theâ€¦ (More)

- Milana Trifkovic, Mehdi Sheikhzadeh, Khaled Nigim, Prodromos Daoutidis
- IEEE Transactions on Control Systems Technology
- 2014

This paper deals with system integration and controller design for power management of a stand-alone renewable energy (RE) hybrid system, which is at the construction stage in Lambton Collegeâ€¦ (More)

- Bhanu Chandra Mulukutla, Andrew Yongky, Prodromos Daoutidis, Wei-Shou Hu
- PloS one
- 2014

The flux of glycolysis is tightly controlled by feed-back and feed-forward allosteric regulations to maintain the body's glucose homeostasis and to respond to cell's growth and energetic needs. Usingâ€¦ (More)