Priyanka Kundur

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BACKGROUND Interleukin-1α (IL-1α) released by dying cells is an alarmin that activates the innate immunity. We hypothesized that after myocardial ischemia-reperfusion (I/R) injury, IL-1α amplifies the myocardial damage by activating the inflammasome and caspase-1. METHODS Adult male CD1 mice were used. The left anterior descending coronary artery was(More)
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