Priyanka Ghosh

  • Citations Per Year
Learn More
The world's worst cholera epidemic in Haiti (2010) coerced to trace the origin and dissemination of the causative agent Vibrio cholerae O1 for proper management of cholera. Sequence analysis of the Haitian strain showed several variations in the genes encoding cholera toxin B subunit (ctxB); toxin-co-regulated pilus (tcpA), repeat in toxins (rtxA),(More)
Three case-patients had emigrated from Romania, and all 5 case-patients lived in the same area of Almeria. These data indicated that the susceptible strain was circulating in the geographic/epi-demiological context of the current case-patient before and when she tested positive for that strain; therefore, she likely acquired the susceptible strain through(More)
Accessory cholera enterotoxin (Ace) of Vibrio cholerae has been shown to contribute to diarrhea. However, the signaling mechanism and specific type of Cl- channel activated by Ace are still unknown. We have shown here that the recombinant Ace protein induced ICl of apical plasma membrane, which was inhibited by classical CaCC blockers. Surprisingly, an(More)
Vibrio cholerae O1 is the etiological agent of the severe diarrheal disease cholera. The bacterium has recently been causing outbreaks in Haiti with catastrophic effects. Numerous mutations have been reported in V. cholerae O1 strains associated with the Haitian outbreak. These mutations encompass among other the genes encoding virulence factors such as the(More)
Priyanka Ghosh, Arindam Naha, Surajit Basak, Santanu Ghosh, T. Ramamurthy, Hemanta Koley, Ranjan K. Nandy, Sumio Shinoda, Haruo Watanabe, Asish K. Mukhopadhyay Division of Bacteriology, National Institute of Cholera and Enteric Diseases (NICED), Kolkata, India; Department of Molecular Biology & Bioinformatics and Bioinformatics Centre, Tripura University,(More)
A novel human ubiquitin conjugating enzyme (UBC) was found to associate with Fas (CD95). The mRNA for this UBC Fas-associated protein (FAP) was widely expressed in human tissues, and the protein was identified in several mammalian cell lines. UBC-FAP shows strong homology to two recently identified UBCs, Hus5 and Ubc9, which control yeast cell cycle(More)
  • 1