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Gene transfer demonstrates that muscle is not a primary target for non-cell-autonomous toxicity in familial amyotrophic lateral sclerosis.

• Timothy M. Miller, Soo Hyun Kim, +8 authors Brian K Kaspar
• Proceedings of the National Academy of Sciences…
• 2006

Amyotrophic lateral sclerosis (ALS) is a fatal, progressive paralysis arising from the premature death of motor neurons. An inherited form is caused by a dominant mutation in the ubiquitously… (More)

Synergy of insulin-like growth factor-1 and exercise in amyotrophic lateral sclerosis.

• Brian K Kaspar, Lindsay Frost, Lindsey J Christian, Priya Umapathi, Fred H. Gage
• Annals of neurology
• 2005

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease of the neuromuscular system resulting in paralysis and ultimately death. Currently, no effective therapy is prescribed for patients;… (More)

Long-term enhancement of skeletal muscle mass and strength by single gene administration of myostatin inhibitors.

• Amanda M Haidet, Liza Rizo, +8 authors Brian K Kaspar
• Proceedings of the National Academy of Sciences…
• 2008

Increasing the size and strength of muscles represents a promising therapeutic strategy for musculoskeletal disorders, and interest has focused on myostatin, a negative regulator of muscle growth.… (More)

Delayed post-irradiation bulbar palsy in nasopharyngeal carcinoma.

• N K Chew, Benson Sim, Chong Tin Tan, K. J. Goh, Norlisah Ramli, Priya Umapathi
• Neurology
• 2001

In a hospital series of 70 patients on follow-up after radiotherapy for nasopharyngeal carcinoma, 14 patients (20%) developed delayed post-irradiation bulbar palsy 1 to 18 years after radiotherapy… (More)

Reverse Phase High Pressure Liquid Chromatographic Determination of Rifampin Quinone and Hydrazone in Anti-tuberculosis Fixed-Dose Formulations Containing Sodium Ascorbate as Anti-oxidant

• Priya Umapathi, Janeesh Plakkal Ayyappan, Darlin S Quine
• 2010

Purpose: To establish the method for the analysis of rifampin quinone and hydrazone in fixeddose combination tablets (FDC) containing rifampicin with or without sodium ascorbate as an additive.… (More)

Optimizing the Redundancy in Wireless Networks Using

• K. Aparna, Priya Umapathi
• 2014

A wireless network sees an explosive growth in past few decades, making adhoc networks as a part of life. In large scale wireless networks information is transmitted in multihop fashion. Multihop may… (More)

Development and Evaluation of a Directly Compressible Co-processed Multifunction Sustained Release Agent for Gliclazide Sustained Release Tablets

• Janeesh Plakkal Ayyappan, Priya Umapathi, Darlin S Quine
• 2010

Directly compressible co-processed sustained release multifunction agent [DCCSRA] comprising povidone and glyceryl behenate in the ratio of 1:1, 1:2 and 1: 3 were prepared and evaluated. The DCCSRA… (More)

An Update on the Utility of Coronary Artery Calcium Scoring for Coronary Heart Disease and Cardiovascular Disease Risk Prediction.

• Sina Kianoush, Mahmoud Al Rifai, +5 authors Michael J. Blaha
• Current atherosclerosis reports
• 2016

Estimating cardiovascular disease (CVD) risk is necessary for determining the potential net benefit of primary prevention pharmacotherapy. Risk estimation relying exclusively on traditional CVD risk… (More)

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