Priya Radhakrishnan

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Growth plate cartilage demonstrates a unique capacity for cell proliferation and matrix synthesis while sustaining mechanical stresses. To test the hypothesis that the extracellular matrices along various depth of growth plate cartilage have different elastic properties, microindentation by atomic force microscopy was applied to en bloc dissected rabbit(More)
Respiratory syncytial virus is a major cause of respiratory disease. There are conflicting accounts of the response of human epithelial cells to respiratory syncytial virus and a lack of data on its effect on ciliary function. Our aim was to study the early stages of respiratory syncytial virus infection of primary human basal and ciliated cultures. Using(More)
RATIONALE Respiratory syncytial virus (RSV) and Streptococcus pneumoniae are major respiratory pathogens. Coinfection with RSV and S. pneumoniae is associated with severe and often fatal pneumonia but the molecular basis for this remains unclear. OBJECTIVES To determine if interaction between RSV and pneumococci enhances pneumococcal virulence. METHODS(More)
In this paper, we report our participation in Knowledge Base Population at TAC 2012. We adopted an Information Retrieval based approach for the Entity Linking and Slot Filling tasks. In Entity Linking we identify potential nodes from the Knowledge Base and then identify the mapping node using tf-idf similarity. We achieved very good performance in the(More)
BACKGROUND The rise in antibiotic-resistant Pseudomonas aeruginosa and the considerable difficulty in eradicating it from patients has re-motivated the study of bacteriophages as a therapeutic option. For this to be effective, host range and viability following nebulization need to be assessed. Host-range has not previously been assessed for the Liverpool(More)
Plasma cell dyscrasias are a group of clinically and biochemically diverse disorders of unknown etiology, characterized by the disproportionate proliferation of one or more clones of B cells, and the presence of a structurally and electrophoretically homogeneous (monoclonal) immunoglobulin or polypeptide subunit in serum or urine. The role of splenectomy in(More)
Given a knowledge base, annotating any text with entities in the knowledge base enhances automated understanding of the text. Entities provide extra contextual information for the automated system to understand and interpret the text better. In the special case when the text is in the form of short text queries, automated understanding can be critical in(More)
Ethanol has been shown to stimulate the beat frequency of respiratory cilia at concentrations encountered during social drinking, while one of its metabolites, acetaldehyde, has been shown to cause a marked decrease in ciliary beat frequency. The aim of this study was to determine whether short-term exposure to ethanol stimulated ependymal cilia and whether(More)
Wikipedia being a large, freely available, frequently updated and community maintained knowledge base, has been central to much recent research. However, quite often we find that the information extracted from it has extraneous content. This paper proposes a method to extract useful information from Wikipedia, using Semantic Features derived from Wikipedia(More)