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Accurate transmission of DNA material from one generation to the next is crucial for prolonged cell survival. Following the discovery of DNA polymerse I in Escherichia coli, the DNA polymerase I class of enzymes has served as the prototype for studies on structural and biochemical mechanisms of DNA replication. Recently, a series of genomic, mutagenesis and(More)
DNA polymerases contain active sites that are structurally superimposable and conserved in amino acid sequence. To probe the biochemical and structure-function relationship of DNA polymerases, a large library (200,000 members) of mutant Thermus aquaticus DNA polymerase I (Taq pol I) was created containing random substitutions within a portion of the dNTP(More)
Escherichia coli DNA polymerase I participates in DNA replication, DNA repair, and genetic recombination; it is the most extensively studied of all DNA polymerases. Motif A in the polymerase active site has a required role in catalysis and is highly conserved. To assess the tolerance of motif A for amino acid substitutions, we determined the mutability of(More)
Image inpainting was historically done manually by painters for removing defect from paintings and photographs. Fill the region of missing information from a signal using surrounding information and reform signal is the basic work of inpainting algorithms. Here in this paper we have studied and reviewed many different algorithms present for doing image(More)
Image Inpainting is technique in which mainly used to filling the region which are damaged and want to recover from unwanted object by collecting the information from the neighbouring pixels. Image inpainting technique has been widely used for reconstructing damaged old photographs and removing unwanted objects from images. In this paper, we present an(More)
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