Pritesh Devbhuti

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A drug may cause alteration in blood-lipid profile and induce lipid peroxidation phenomena on administration in the body. Antioxidant may play beneficial role to control the negative alteration in lipid profile and lipid peroxidation. In view of this context, the present in vivo study was carried out to evaluate the role of ascorbic acid as antioxidant on(More)
The plant Bryophyllum calycinum Salisb. (Crassulaceae ) is a shrub mainly found in the tropical parts of Bengal and in southern Africa and American continents. It is locally known as ìPatharkuchiì and for long has been used in Ayurvedic medicine. As per traditional use, the leaves and leaf juice are used as antiviral, antipyretic, antimicrobial,(More)
Lipid peroxidation is the oxidative deterioration of polyunsaturated fatty acids (PUFAs), which is a free radical related process. Studies showed that reactive oxygen species (ROS) are involved in a diversity of biological phenomena including atherosclerosis, neurodegenerative diseases, carcinogenesis etc. ROS and other pro-oxidant agents have the capacity(More)
The stems of Tinospora tomentosa Miers. are used in Indian system of medicine. The present study deals with the preliminary qualitative phytochemical investigation and acute toxicity study on various extracts of the plant. The acute toxicity was studied in mice and rats in terms of 24 h LD50 of the methanol and aqueous extracts. These extracts were found to(More)
The term plasma lipid profile considers measurement of certain components of plasma including total cholesterol (TCh), high density lipoprotein cholesterol (HDL-Ch), triglycerides (Tg), low density blipoprotein cholesterol (LDL-Ch) and very low density lipoprotein cholesterol (VLDL-Ch). TCh consists of all the cholesterol present in different lipoproteins(More)
Alteration of plasma lipid profile and induction of lipid peroxidation may take place due to drug effect, which may be correlated with adverse drug reactions and drug-induced toxicity. Considering this fact, the present in vivo study was carried out to evaluate the effect of clindamycin on plasma lipid profile and peroxidation parameters alone and in(More)
Extent of drug-induced peroxidation of plasma lipids can be estimated by measuring the peroxidation parameters of blood plasma like MDA, HNE, GSH, NO, etc content after drug administration. Lipid peroxidation, the oxidative deterioration of polyunsaturated lipids, is a highly destructive process that induces a wide variety of changes in cellular membranes(More)
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