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QbD-based systematic development of novel optimized solid self-nanoemulsifying drug delivery systems (SNEDDS) of lovastatin with enhanced biopharmaceutical performance
Abstract Of late, solid self-nanoemulsifying drug delivery systems (S-SNEDDS) have been extensively sought-after owing to their superior portability, drug loading, stability and patient compliance.Expand
QbD-Driven Development and Validation of a HPLC Method for Estimation of Tamoxifen Citrate with Improved Performance.
The current studies entail Quality by Design (QbD)-enabled development of a simple, rapid, sensitive and cost-effective high-performance liquid chromatographic method for estimation of tamoxifenExpand
Novel surface-engineered solid lipid nanoparticles of rosuvastatin calcium for low-density lipoprotein-receptor targeting: a Quality by Design-driven perspective.
AIM The present studies describe Quality by Design-oriented development and characterization of surface-engineered solid lipid nanoparticles (SLNs) of rosuvastatin calcium for low densityExpand
Cellulose Derivatives as Thermoresponsive Polymer: An Overview.
Cellulose is a linear homopolymer polysaccharide having water insoluble property. Various cellulose derivative prepared by etherification gains water solubility and shows thermoresponsive gelation.Expand
Recent advances in self-emulsifying drug delivery systems (SEDDS).
TLDR
This paper provides an updated bird's-eye view account on the publications and patents of diverse oral and non-oral self-emulsifying (SE) systems not only of various synthetic and semisynthetic drugs, but also of several phytopharmaceuticals, nutraceuticals and biological macromolecules. Expand
Novel dietary lipid-based self-nanoemulsifying drug delivery systems of paclitaxel with p-gp inhibitor: implications on cytotoxicity and biopharmaceutical performance
Objectives: This work describes the development and characterization of novel self-nanoemulsifying drug delivery systems (SNEDDS) employing polyunsaturated fatty acids for enhancing the oralExpand
Natural lipids enriched self-nano-emulsifying systems for effective co-delivery of tamoxifen and naringenin: Systematic approach for improved breast cancer therapeutics.
The nano-miceller drug delivery carriers of tamoxifen (TMX) having natural ingredients like polyunsaturated fatty acid (PUFA) with self-nano-emulsifying properties was developed with naringenin (NG)Expand
Surface-tailored nanomixed micelles containing quercetin-salicylic acid physical complex for enhanced cellular and in vivo activities: a quality by design perspective.
AIM The development of surface-tailored quercetin (QCT)-salicylic acid (SA) physical complex for effective treatment of skin carcinoma. MATERIALS & METHODS QCT-SA nanomixed micelles were preparedExpand
Analytical QbD-based systematic bioanalytical HPLC method development for estimation of quercetin dihydrate
ABSTRACT The current work entails development of rapid, sensitive, and inexpensive high-performance liquid chromatographic method of quercetin dihydrate using the quality by design approach. QualityExpand
SOLUBILITY ENHANCEMENT BY SOLVENT DEPOSITION TECHNIQUE: AN OVERVIEW
Most of the drugs being discovered with potential therapeutic effect are water insoluble in nature due to which they are poorly absorbed from the site of administration. With number of solubilityExpand
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