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Long-term adherence to statins is poor. We assessed the relationship between cardiovascular (CV) risk and atorvastatin adherence in primary- and secondary-prevention patients, adjusting for healthy-adherer bias by incorporating preventive service use into the model. Medical and pharmacy claims from employee-based plans from 2002 to 2008 were analyzed for(More)
Exosomes are multivesicular bodies formed by inverse membrane budding into the lumen of an endocytic compartment. Fusion with the plasma membrane leads to their release into the external milieu. The incorporation of heat shock proteins into exosomes has been associated with immune regulatory activity. We have examined whether heat shock protein-containing(More)
OBJECTIVE To assess outcomes associated with oral anti-diabetic drug (OAD) treatment concordant with guidelines from the National Kidney Foundation (NKF) among type 2 diabetes mellitus (T2DM) patients with chronic kidney disease (CKD). METHODS Electronic health record data between 1/1/2005 and 10/31/2010 provided by an integrated health system were(More)
BACKGROUND Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia and disproportionately affects the elderly. OBJECTIVE This study describes patient characteristics and caregiver assistance among Medicare beneficiaries with AF and examines factors associated with receiving anticoagulant treatment. METHODS Patients with AF and(More)
To the Editor: Control of communicable diseases often relies in part on school and workplace exclusion. Exclusion policies are also likely to play a role in pandemic infl uenza control and currently are used as policy for control of several vaccine-preventable diseases, including mumps (1). Mumps virus is typically present in saliva from 2–3 days before to(More)
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