Preet Kamal Dhillon

Learn More
The worldwide rates for histology- and subsite-specific types of esophageal and gastric cancer reveal strikingly divergent patterns. The contribution of environmental and genetic factors has been explored in several high-incidence areas, but data on genetic influences are scarce for Western countries. Using data from a multicenter, population-based,(More)
BACKGROUND Adiponectin, an insulin-sensitizing adipokine, is inversely associated with adiposity and prostate cancer risk and progression. However, the role of genetic variation in the adiponectin (ADIPOQ) and receptor genes (ADIPOR1/R2) in prostate cancer is largely unknown. METHODS In a nested case-control study of 1,286 cases and 1,267 controls within(More)
Experimental and clinical data suggest that aspirin and other nonsteroidal inflammatory drugs may delay the progression of prostate cancer through inhibition of the COX pathway and its effects on cellular proliferation, apoptosis, and angiogenesis. Epidemiologic data support a reduced risk of prostate cancer incidence with aspirin use, yet no evidence(More)
Experimental studies suggest a role for aspirin in the chemoprevention of prostate cancer and epidemiological evidence supports a modest inverse association between regular aspirin use and prostate cancer risk, especially for advanced disease. In a prospective cohort study of 51,529 health professionals aged 40-75 years at baseline, we evaluated long-term(More)
Endometriosis, defined by implantation of endometrial tissue outside the uterus, is commonly found on the ovaries and is characterized by a range of symptoms and severity, including chronic pelvic pain and infertility. The role of modifiable exogenous factors such as exercise in the development of this disease is not well understood. The authors conducted a(More)
Protein expression of p63 is used to differentiate prostate cancer from benign mimickers. Recent studies suggest that it may also distinguish aggressive prostate cancer with down-regulated expression occurring in men with more advanced disease. We conducted a prospective study among 298 men ages 51 to 84 years who were diagnosed with prostate cancer in the(More)
BACKGROUND α-Methylacyl-CoA racemase (AMACR) is an enzyme that serves as a diagnostic biomarker of prostate cancer in clinical practice. Recent studies suggest that low AMACR expression is associated with biochemical recurrence and the development of fatal disease. METHODS We conducted a prospective cohort study among 920 men aged 47-84 years, who were(More)
A case-control study of the efficacy of cancer screening, like any other case-control study, must deal with potential confounding. There are 2 categories of confounding variables that pose special problems for studies of screening: (1) age and calendar time resulting from different temporal distributions of screening between cases and controls irrespective(More)
The design of software systems can exhibit several problems which can be either due to inefficient analysis and design during the initial construction of the software or more often, due to software ageing, where software quality degenerates over time. The design problems appear as "bad smells" at code or design level and the process of removing them is(More)
Breast Cancer is considered as one of the major causes for the increase in mortality among women. Computerized Mammography helps radiologists as a second reader in diagnosing the abnormalities. This paper aims to detect the masses of the Digital Mammograms. In this approach, the mammogram is subjected to morphological pre-processing, artifacts removal,(More)
  • 1