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PURPOSE To evaluate inter- and intrareader agreement in breast percent density (PD) estimation on clinical digital mammograms and central digital breast tomosynthesis (DBT) projection images. MATERIALS AND METHODS This HIPAA-compliant study had institutional review board approval; all patients provided informed consent. Breast PD estimation was performed(More)
RATIONALE AND OBJECTIVES The poor specificity of galactography, the imaging modality generally indicated in cases of nipple discharge, has led to a large number of biopsies with negative results. A quantitative scheme for classifying galactographic findings might help reduce the number of such biopsies in the future. As a first step toward that goal, the(More)
In this paper we propose using histogram intersection for mammographic image classification. First, we use the bag-of-words model for image representation, which captures the texture information by collecting local patch statistics. Then, we propose using normalized histogram intersection (HI) as a similarity measure with the K-nearest neighbor (KNN)(More)
PURPOSE To correlate the parenchymal texture features at digital breast tomosynthesis (DBT) and digital mammography with breast percent density (PD), an established breast cancer risk factor, in a screening population of women. MATERIALS AND METHODS This HIPAA-compliant study was approved by the institutional review board. Bilateral DBT images and digital(More)
PURPOSE Develop a technique to fabricate a 3D anthropomorphic breast phantom with known ground truth for image quality assessment of 2D and 3D breast x-ray imaging systems. METHODS The phantom design is based on an existing computer model that can generate breast voxel phantoms of varying composition, size, and shape. The physical phantom is produced in(More)
A method is proposed for generating synthetic mammograms based upon simulations of breast tissue and the mammographic imaging process. A computer breast model has been designed with a realistic distribution of large and medium scale tissue structures. Parameters controlling the size and placement of simulated structures (adipose compartments and ducts)(More)
A method is proposed for realistic simulation of the breast ductal network as part of a computer three-dimensional (3-D) breast phantom. The ductal network is simulated using tree models. Synthetic trees are generated based upon a description of ductal branching by ramification matrices (R matrices), whose elements represent the probabilities of branching(More)