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OBJECTIVE To determine the long-term objective and subjective outcomes of use of a porcine skin graft (Pelvicol) compared with conventional colporrhaphy in recurrent pelvic organ prolapse surgery and to analyze risk factors and safety. DESIGN Open randomized controlled multicenter study. SETTING Eight Swedish hospitals. POPULATION 135 consecutive(More)
OBJECTIVE To determine whether the day-by-day postoperative recovery differs between women undergoing subtotal and total abdominal hysterectomy, and to analyse factors associated with postoperative recovery and sick leave. DESIGN A prospective, open, randomised multicentre trial. SETTING Seven hospitals and one private clinic in the south-east of(More)
OBJECTIVE To determine whether postoperative symptoms differ between women who undergo abdominal benign hysterectomy in a fast-track model under general anesthesia or spinal anesthesia with intrathecal morphine. DESIGN Secondary analysis from a randomized, open, multicenter study. SETTING Five hospitals in south-east Sweden. POPULATION One-hundred and(More)
OBJECTIVE The aim of this prospective observational study was to investigate the gynecological and defecographic features in women with stress urinary incontinence operated with Burch colposuspension in order to analyze if the findings could predict subsequent development of genital prolapse. SUBJECT Twenty-one women with urodynamically proven genuine(More)
OBJECTIVES To determine whether the day-by-day recovery of general wellbeing was faster in women undergoing laparoscopic hysterectomy than in total abdominal hysterectomy and to analyse the association between stress coping and sick-leave and the day-by-day recovery measured as general wellbeing. STUDY DESIGN A randomised multicentre trial conducted in(More)
OBJECTIVE To compare subtotal abdominal hysterectomy (SH) and total abdominal hysterectomy (TH) regarding influence on postoperative psychological wellbeing and surgical outcome measurements. DESIGN A prospective, open, randomised multicentre trial. SETTING Seven hospitals and one private clinic in the south-east of Sweden. POPULATION Two-hundred(More)
OBJECTIVE We studied the activity and regulation of the peroxisome proliferator-activated receptor-gamma response element (PPRE) in primary human adipocytes. METHODS We transfected primary human adipocytes with a plasmid-encoding firefly luciferase cDNA under control of a PPRE from the acyl-coenzyme A oxidase gene by using our newly developed(More)
OBJECTIVE To determine if maternal age (35 years of age or older) in primiparous women is a risk factor for the development of obstetric anal sphincter rupture (OASR) and to identify obstetric factors associated with it. MATERIAL AND METHODS This is a retrospective case-control study. The study population was made up of the 5,345 primiparous women aged(More)
BACKGROUND The aim of this study is to investigate the long-term efficacy of the Burch colposuspension and to analyze the risk factors for an unsuccessful outcome at the long-term follow-up of more than 10 years. METHODS Data from patient files of 190 women on whom surgery was performed with Burch colposuspension during 1980-1988 and answers from a postal(More)
BACKGROUND Fast-track regimen has been shown to reduce postoperative complications in gastrointestinal surgery. AIMS We investigated the incidence and type of postoperative complications and associated risk factors after benign abdominal hysterectomy undertaken in a fast-track program. METHODS A prospective longitudinal cohort study. In five Swedish(More)