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Journals and Conferences
BACKGROUND Myocardial injury after noncardiac surgery (MINS) was defined as prognostically relevant myocardial injury due to ischemia that occurs during or within 30 days after noncardiac surgery. The study's four objectives were to determine the diagnostic criteria, characteristics, predictors, and 30-day outcomes of MINS. METHODS In this international,… (More)
The HLA-A, B, C and DR antigens were determined in a group of 100 blacks with classical or definite rheumatoid arthritis (RA) in Durban, South Africa. Fifty-six of these patients were also tested for the DQ antigens. There was a significant association of HLA-DR4 with RA (chi 2 = 77.2; p less than 0.0001). The frequency of DR4 in RA was 44% in comparison… (More)
A retrospective study was carried out to determine the frequency, age of onset, mode of presentation, pattern of joint involvement, and incidence of primary and secondary gout in black patients with gout who were admitted to the King Edward VIII Hospital in Durban, South Africa. Nineteen patients were admitted to hospital with gout over a 5-year period from… (More)
OBJECTIVES To determine the proportion of noncardiac surgery patients exceeding the published 99th percentile or change criteria with the high sensitivity Troponin T (hs-TnT) assay. DESIGN AND METHODS We measured hs-TnT preoperatively and postoperatively on days 1, 2 and 3 in 325 adults. RESULTS Postoperatively 45% (95% CI: 39-50%) of patients had… (More)
The aim of this study was to determine whether measurement of pre-operative brain natriuretic peptide can significantly improve risk stratification of vascular surgical patients. The study endpoint was postoperative raised troponins. Net reclassification improvement was determined for risk categories based on the Revised Cardiac Risk Index. Two… (More)
BACKGROUND Recent evidence suggests that application of the Revised Cardiac Risk Index (RCRI) for peri-operative cardiovascular risk stratification in vascular surgery patients may be inappropriate, necessitating the development of risk indices specific to vascular surgery patients. OBJECTIVES To identify risk factors for cardiovascular morbidity and… (More)
Risk factors for peri-operative cardiac morbidity are poorly described in HIV-positive patients. This prospective observational study describes cardiovascular risk factors in a cohort of vascular surgical patients of known HIV status. We recruited 225 patients with 73 (32%) being HIV-positive. When compared with HIV-negative patients, the HIV-positive… (More)
This article reports some observations made in a woman who developed myasthenia gravis after treatment with D-penicillamine. Withdrawal of the drug was not followed by spontaneous remission of the myasthenic syndrome.
Only 1 case of systemic lupus erythematosus (SLE) has been documented in a South African Black man. We report 3 further patients, 1 each from Cape Town, Durban and East London, diagnosed between 1978 and 1982. All 3 patients fulfilled the revised American Rheumatism Association criteria for the classification of SLE.
A 42-year-old Indian woman with long-standing rheumatoid arthritis became pregnant. Exacerbation of her arthritis during pregnancy and in the puerperium is described and mechanisms for the deterioration in her condition are postulated. Two months after delivery, thyrotoxicosis was suspected because of marked weight loss. Initially the interpretation of her… (More)