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  • Tadashi Sawada, Lydia A. Falk, Praveen P. Nekkar Rao, William J. Murphy, Dov H. Pluznik
  • Biology, Medicine
  • Journal of immunology
  • 1997 (First Published: 1 June 1997)
  • Macrophage inducible nitric oxide synthase (iNOS) catalyzes the synthesis of NO. IL-6-stimulated macrophage differentiation of murine myeloid M1 cells is accompanied by iNOS gene induction andContinue Reading
  • Tarek Said Mohamed, Jacky C K Yeung, Praveen P. Nekkar Rao
  • Chemistry, Medicine
  • Bioorganic & medicinal chemistry letters
  • 2011 (First Published: 1 October 2011)
  • A group of 2-substituted N-(naphth-1-ylmethyl)pyrimidin-4-amines (6a-k) and N-benzhydrylpyrimidin-4-amines (7a-k) in conjunction with varying steric and electronic properties at the C-2 position wereContinue Reading
  • Praveen P. Nekkar Rao, Lydia A. Falk, S F Dougherty, Tadashi Sawada, Dov H. Pluznik
  • Biology, Medicine
  • Journal of immunology
  • 1997 (First Published: 1 October 1997)
  • Activation of macrophages by LPS and taxol results in production of IL-1, IL-6, TNF-alpha, and granulocyte-macrophage CSF (GM-CSF), which are involved in regulating hemopoiesis, inflammation, andContinue Reading
  • Tarek Said Mohamed, Wesseem Osman, Gary Tin, Praveen P. Nekkar Rao
  • Chemistry, Medicine
  • Bioorganic & medicinal chemistry letters
  • 2013 (First Published: 1 August 2013)
  • The commonly used beverage and psychostimulant caffeine is known to inhibit human acetylcholinesterase enzyme. This pharmacological activity of caffeine is partly responsible for its cognitionContinue Reading
  • Tarek Said Mohamed, Jacky C K Yeung, Maryam S. Vasefi, Michael A Beazely, Praveen P. Nekkar Rao
  • Chemistry, Medicine
  • Bioorganic & medicinal chemistry letters
  • 2012 (First Published: 1 July 2012)
  • We investigated a group of 2-benzylpiperidin-N-benzylpyrimidin-4-amines with various electron-withdrawing or electron-donating groups (EWGs or EDGs, respectively) as multi-targeted Alzheimer'sContinue Reading