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Wavelet transforms originated in geophysics in the early 1980s for the analysis of seismic signals. Since then, significant mathematical advances in wavelet theory have enabled a suite of applications in diverse fields. In geophysics the power of wavelets for analysis of nonstationary processes that contain multiscale features, detection of singularities,(More)
Regulation of microtubule dynamics is essential for many cell biological processes and is likely to be variable between different subcellular regions. We describe a computational approach to analyze microtubule dynamics by detecting growing microtubule plus ends. Our algorithm tracked all EB1-EGFP comets visible in an image time-lapse sequence allowing the(More)
Polarity of the microtubule (MT) cytoskeleton is essential for many cell functions. Cytoplasmic linker-associated proteins (CLASPs) are MT-associated proteins thought to organize intracellular MTs and display a unique spatiotemporal regulation. In migrating epithelial cells, CLASPs track MT plus ends in the cell body but bind along MTs in the lamella. In(More)
The aim of the study was to induce B deficiency symptoms and to relate the generation of reactive oxygen species (ROS) and altered cellular redox environment with the effects of B deficiency in mulberry (Morus alba L.) cv. Kanva-2 plants. Study was undertaken on antioxidant responses, malondialdehyde (MDA) content as an indicator of oxidative damage and(More)
A new method is presented for quantifying proteomic and metabolomic profile data by liquid chromatography-mass spectrometry (LC-MS) with electrospray ionization. This biotechnology provides differential expression measurements and enables the discovery of biological markers (biomarkers). Work presented here uses human serum but is applicable to any fluid or(More)
We explain why adverse asset shocks after good economic times lead to a sudden drying-up of liquidity. Financial firms raise short-term debt to finance asset purchases; this induces risk-shifting when economic conditions worsen and limits their ability to roll over debt. Constrained firms de-lever by selling assets to lower-leverage firms. In turn,(More)
BACKGROUND Although newborn screening for critical congenital heart disease (CCHD) was recommended by the US Health and Human Services Secretary's Advisory Committee on Heritable Disorders in Newborns and Children to promote early detection, it was deemed by the Secretary of the HHS as not ready for adoption pending an implementation plan from HHS agencies.(More)
Target Tracking as it moves through a sensor network has become an increasingly important application in Wireless Sensor Networks. This paper examines some of the target tracking techniques in use today. An analysis of each technique is presented along with it advantages, problems and possible improvements. There are seven main categories explored in this(More)
for helpful comments, and especially to Siddhartha Chib for his advice and encouragement, and an anonymous referee for insightful suggestions that have substantially improved the article. This paper was previously circulated under the title " The Economic Value of Volatility Modeling: Asset Allocation with a High Dimensional Dynamic Latent Factor(More)
This paper addresses two questions: (i) can factor content of trade be used to measure the effect of trade on wage inequality in a given year, with tastes and technology constant; and (ii) can it be used to measure the contribution of trade to the change in wage inequality between two years, with tastes and technology allowed to change? Deardorff and(More)