Pratap N. Kumar

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Approximately half the excitatory neurons in layer 6 (L6) of the rat barrel cortex project to the thalamus with axon collaterals ramifying in the granular L4; the remaining project within cortex with collaterals restricted to infragranular laminae. In analogy, L6 inhibitory neurons also include locally arborizing and inter-laminar projecting neurons. We(More)
There has been growing interest in understanding energy metabolism in human embryos generated using assisted reproductive techniques (ART) for improving the overall success rate of the method. Using NMR spectroscopy as a noninvasive tool, we studied human embryo metabolism to identify specific biomarkers to assess the quality of embryos for their(More)
OBJECTIVE To test whether sperm with abnormal head morphology are more likely to undergo DNA damage and/or chromatin modification during the process of freeze-thawing. DESIGN In this prospective study, the semen samples from forty-four men attending the infertility clinic were included. Samples were divided into aliquots to allow direct comparison of(More)
OBJECTIVES (1) To determine the frequency of maternal near miss, maternal near miss incidence ratio (MNMR), maternal near miss to mortality ratio and mortality index. (2) To compare the nature of near miss events with that of maternal mortality. (3) To see the trend of near miss events. DESIGN Audit. SETTING Kasturba Hospital, Manipal University,(More)
Lipomatous tumors of the uterus are rare neoplasms which can be divided into three broad groups - pure, mixed, and the exceedingly rare malignant liposarcoma. Lipoleiomyoma is a rare benign variant of leiomyoma with an incidence ranging between 0.03% and 0.2%. These tumors are usually seen in obese postmenopausal women and are usually asymptomatic but may(More)
The endocrinology of human pregnancy involves endocrine and metabolic changes that result from physiological alterations at the boundary between mother and fetus. Progesterone and oestrogen have a great role along with other hormones. The controversies of use of progestogen and others are discussed in this chapter. Progesterone has been shown to stimulate(More)
In this era of minimal intervention dentistry, the changing concept of cavity preparation and the introduction of reliable adhesive materials have lead to the development of alternative methods of caries removal. Chemo mechanical caries removal (CMCR) involves the chemical softening of the carious dentine, followed by its removal with gentle excavation.(More)
BACKGROUND The effects of exercise, metformin, and orlistat on anthropometric parameters, lipid profile, endocrine parameters, and ovulation in polycystic ovarian syndrome (PCOS) women were compared. AIM The aim was to study the efficacy of orlistat compared with metformin and exercise in PCOS. DESIGN Randomized control trial. METHODS A total of 90(More)
OBJECTIVE To examine the fertilizing ability and DNA damage response of preimplantation stage embryos derived from the γ-irradiated mouse sperm carrying varying amounts of DNA strand-breaks. MATERIAL AND METHODS The DNA damage in the sperm was induced by exposing the testicular area to different doses of γ-radiation. After mating with healthy female mice,(More)
This study evaluated the effect of vitamin E supplementation to cryoprotective media on post-thaw motility and DNA integrity of normozoospermic and asthenozoospermic semen samples. The results of this study indicate that supplementation of vitamin E (5 mM) significantly improves the post-thaw motility and DNA integrity in normozoospermic and(More)