Prashanth Rao

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BACKGROUND The main aims of managing thoracolumbar fractures involve stabilization of traumatized regions, to promote vertebral healing or segmental fusion. Recently, percutaneous pedicle screw fixation has evolved as an alternative approach for the treatment of thoracolumbar fractures, aiming to minimize soft tissue injury and perioperative morbidity. A(More)
OBJECT The purpose of this study was to evaluate the usefulness of preoperative magnetic resonance spectroscopy (MRS) in neurosurgical patients with diagnostically challenging intracranial lesions. METHODS Included in this study are twenty-three consecutive patients presenting to the neurosurgery service with diagnostically challenging intracranial(More)
OBJECT The development of minimally invasive surgical techniques is driven by the quest for better patient outcomes. There is some evidence for the use of minimally invasive surgery for degenerative lumbar spine stenosis (LSS), but there are currently no studies comparing outcomes with matched controls. The object of this study was to compare outcomes(More)
BACKGROUND Surgical clipping and endovascular coiling yield similar functional outcomes for the treatment of saccular aneurysms of the anterior communicating (ACOM) artery. However, surgical treatment may be associated with greater rates of cognitive impairment due to injury of adjacent structures. We aimed to quantify the rates of injury(More)
Anterior lumbar interbody fusion (ALIF) has become a widely recognized surgical technique for degenerative pathology of the lumbar spine. Spinal fusion has evolved dramatically ever since the first successful internal fixation by Hadra in 1891 who used a posterior approach to wire adjacent cervical vertebrae in the treatment of fracture-dislocation.(More)
Degenerative disc and facet joint disease of the lumbar spine is common in the ageing population, and is one of the most frequent causes of disability. Lumbar spondylosis may result in mechanical back pain, radicular and claudicant symptoms, reduced mobility and poor quality of life. Surgical interbody fusion of degenerative levels is an effective treatment(More)
The clinical outcome of lumbar spinal fusion is correlated with achievement of bony fusion. Improving interbody implant bone on-growth and in-growth may enhance fusion, limiting pseudoarthrosis, stress shielding, subsidence and implant failure. Polyetheretherketone (PEEK) and titanium (Ti) are commonly selected for interbody spacer construction. Although(More)
STUDY DESIGN Systematic review and meta-analysis. OBJECTIVE To review and assess the current evidence from the literature on the potential association between disc infection with the development of symptomatic degenerative disc disease. SUMMARY OF BACKGROUND DATA The potential relationship between disc infection- and disc degeneration-related symptoms(More)
BACKGROUND There is limited information on clinical outcomes after anterior lumbar interbody fusion (ALIF) based on the indications for surgery. OBJECTIVE To compare the clinical and radiological outcomes of ALIF for each surgical indication. METHODS This prospective clinical study included 125 patients who underwent ALIF over a 2-year period. The(More)
BACKGROUND CONTEXT A frequently quoted advantage of anterior lumbar interbody fusion (ALIF) is indirect foraminal decompression, although there are few studies substantiating this statement. Also, there are no clinical studies using a standardized method to measure the foraminal area (FA) and the correlation with disc height (DH) parameters. This study is(More)