Prasant Mohanty

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OBJECTIVES This study investigated the left atrial appendage (LAA) by computed tomography (CT) and magnetic resonance imaging (MRI) to categorize different LAA morphologies and to correlate the morphology with the history of stroke/transient ischemic attack (TIA). BACKGROUND LAA represents one of the major sources of cardiac thrombus formation responsible(More)
OBJECTIVES The purpose of this study was to evaluate the feasibility and safety of periprocedural dabigatran during atrial fibrillation (AF) ablation. BACKGROUND AF ablation requires optimal periprocedural anticoagulation for minimizing bleeding and thromboembolic complications. The safety and efficacy of dabigatran as a periprocedural anticoagulant for(More)
BACKGROUND Longstanding persistent (LSP) atrial fibrillation (AF) is the most challenging type of AF. In addition to pulmonary vein isolation, substrate modification and triggers ablation have been reported to improve freedom from AF in patients with LSPAF. OBJECTIVES This study sought to assess whether the empirical electrical isolation of the left(More)
BACKGROUND Periprocedural thromboembolic and hemorrhagic events are worrisome complications of catheter ablation for atrial fibrillation (AF). The periprocedural anticoagulation management could play a role in the incidence of these complications. Although ablation procedures performed without warfarin discontinuation seem to be associated with lower(More)
BACKGROUND Together with pulmonary veins, many extrapulmonary vein areas may be the source of initiation and maintenance of atrial fibrillation. The left atrial appendage (LAA) is an underestimated site of initiation of atrial fibrillation. Here, we report the prevalence of triggers from the LAA and the best strategy for successful ablation. METHODS AND(More)
BACKGROUND Periprocedural anticoagulation management with uninterrupted warfarin and a "therapeutic" international normalized ratio is the best approach for reducing both thromboembolic and bleeding complications in the setting of catheter ablation for atrial fibrillation (AF). OBJECTIVE The purpose of this study was to evaluate the safety and feasibility(More)
BACKGROUND Radiofrequency catheter ablation of atrial fibrillation can be performed under general anesthesia or conscious sedation at the physician's preference. OBJECTIVE We randomized a series of consecutive patients with paroxysmal atrial fibrillation (AF) undergoing radiofrequency catheter ablation to either general anesthesia or conscious sedation to(More)
OBJECTIVES The aim of this study was to investigate impact of metabolic syndrome (MS) on outcomes of catheter ablation in patients with atrial fibrillation (AF) in terms of recurrence and quality of life (QoL). BACKGROUND MS, a proinflammatory state with hypertension, diabetes, dyslipidemia, and obesity, is presumed to be a close associate of AF. (More)
Luigi Di Biase, MD, PhD; David Burkhardt, MD; Pasquale Santangeli, MD; Prasant Mohanty, MPH, MBBS; Javier Sanchez, MD; Rodney Horton, MD; G. Joseph Gallinghouse, MD; Sakis Themistoclakis, MD; Antonio Rossillo, MD; Dhanunjaya Lakkireddy, MD; Madhu Reddy, MD; Steven Hao, MD; Richard Hongo, MD; Salwa Beheiry, RN; Jason Zagrodzky, MD; Rong Bai, MD; Sanghamitra(More)
BACKGROUND Catheter ablation of atrial fibrillation is associated with the potential risk of periprocedural stroke, which can range between 1% and 5%. We developed a prospective database to evaluate the prevalence of stroke over time and to assess whether the periprocedural anticoagulation strategy and use of open irrigation ablation catheter have resulted(More)