Learn More
BACKGROUND Large comparative genomics studies and tools are becoming increasingly more compute-expensive as the number of available genome sequences continues to rise. The capacity and cost of local computing infrastructures are likely to become prohibitive with the increase, especially as the breadth of questions continues to rise. Alternative computing(More)
In this overview to biomedical computing in the cloud, we discussed two primary ways to use the cloud (a single instance or cluster), provided a detailed example using NGS mapping, and highlighted the associated costs. While many users new to the cloud may assume that entry is as straightforward as uploading an application and selecting an instance type and(More)
MOTIVATION Prior to applying genomic predictors to clinical samples, the genomic data must be properly normalized to ensure that the test set data are comparable to the data upon which the predictor was trained. The most effective normalization methods depend on data from multiple patients. From a biomedical perspective, this implies that predictions for a(More)
A recent study of the replicability of key psychological findings is a major contribution toward understanding the human side of the scientific process. Despite the careful and nuanced analysis reported, the simple narrative disseminated by the mass, social, and scientific media was that in only 36% of the studies were the original results replicated. In(More)
In this paper, a fragile watermarking scheme is proposed for Tamper Detection in images. Here, watermark is derived from the original host image, which is consists of reference-bits and check-bits and is embedded into the host image using a lossless data-hiding technique. On the receiver side, one can attempt to extract the watermark bits and recover the(More)
Background: Prior to applying genomic predictors to clinical samples, the genomic data must be properly normalized. The most effective normalization methods depend on the data from multiple patients. From a biomedical perspective this implies that predictions for a single patient may change depending on which other patient samples they are normalized with.(More)
Mobile device users use their devices any time anywhere. Hence there are different constraints we discussed on routing in MANET. Several routing protocols have been proposed in recent years for deployment of MANET. There are three types of MANET routing protocols reactive, proactive and hybrid. In this paper we have analyzed all these approaches and(More)
In recent years, a lot of research is focused on wireless adhoc network, which is focused on field of performance, security, and energy. This paper addressed the difficulties and challenges facing the adhoc networks in security. Transmission of extremely sensitive information via one single path is not advisable as the information can easily be lost or(More)
This paper demonstrates a method to identify keyword strategies to facilitate the search for articles containing decision support and clinical algorithms represented in the text by complex unsearchable items such as decision tree figures, pseudo code, or mathematical formulae. We use a text mining approach to generate 'Surrogate Algorithm Tags' (SRATs),(More)
Although a protocol aims to guide treatment management and optimize overall outcomes, the benefits and harms for each individual vary due to heterogeneity. Some protocols integrate clinical and genetic variation to provide treatment recommendation; it is not clear whether such integration is sufficient. If not, treatment outcomes may be sub-optimal for(More)