Pranjal Srivastava

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This paper investigates delay, power and area of several critical library components for high-performance, lowpower microprocessor designs. To improve performance of a 0.18~pm technology at a supply voltage of 1.8 I( the proposed hybrid dual-V’ (HDVT) circuit architectures enhance speed of high-v, by 21% while reducing leakage power dissipation of low-Vt by(More)
BACKGROUND Obesity is an increasingly important health problem worldwide as well as in developing countries like India. Recent genetic studies suggest that obesity associated FTO and IRX3 are functionally linked and many effects due to genetic variants in FTO gene act through IRX3. AIM To evaluate the association of FTO and IRX3 genetic variants towards(More)
BACKGROUND Obesity is a multi-factorial disorder influenced by genetic and environmental factors. The physiological pathways associated with obesity are complex and involve several genes. AIM The aim of this survey is to evaluate the association of genetic variants of melanocortin-4-receptor (MC4R), pro-opiomelanocortin (POMC), apolipoprotein E (APOE) and(More)
Background Obesity is a very common disorder resulting from an imbalance between food intake and energy expenditure, and it has a substantial impact on the development of chronic diseases. The aim of this study was to examine the association of INSIG2 (rs7566605) gene polymorphism with obesity and obesity associated phenotypes in North Indian subjects. (More)
Normal human pregnancy is associated wi th physiological blood changes, namely, neutrophilic leukocytosis, hyperlipidemia and procoagulant, hypof ibr ino ly t ic and in f lammatory condi t ions. Preeclampsia (PE), a pregnancy-specific disorder characterized clinically by new onset hypertension and proteinuria after 20 wk of gestation, is the most frequently(More)
OBJECTIVES The aim of the study was to investigate the association of 55 SNPs in 28 genes with obesity risk in a North Indian population using a multianalytical approach. METHODS Overall, 480 subjects from the North Indian population were studied using strict inclusion/exclusion criteria. SNP Genotyping was carried out by Sequenom Mass ARRAY platform(More)
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