• Publications
  • Influence
Nitric Oxide Production by Necrotrophic Pathogen Macrophomina phaseolina and the Host Plant in Charcoal Rot Disease of Jute: Complexity of the Interplay between Necrotroph–Host Plant Interactions
TLDR
Interestingly, M. phaseolina was found to produce nitric oxide which was detected in vitro inside the mycelium and in the surrounding medium and may have important physiological significance in necrotrophic host pathogen interaction. Expand
Regulation of cell cycle and stress responses under nitrosative stress in Schizosaccharomyces pombe.
TLDR
A novel molecular mechanism of cell cycle control under nitrosative stress is proposed based on the experimental results and bioinformatics analysis of the fission yeast Schizosaccharomyces pombe. Expand
The extracellular role of DNA damage repair protein APE1 in regulation of IL-6 expression.
TLDR
It is found that monocytes secrete APE1 upon inflammatory challenges and it is shown that APE 1 is secreted through extracellular vesicles formation via endosomal sorting complex required for transport (ESCRT)-dependent pathway. Expand
Global transcriptomic profiling of Schizosaccharomyces pombe in response to nitrosative stress.
TLDR
Genes of the pathway meiosis, cell cycle, spliceosome and oxidative phosphorylation were mostly affected under nitrosative stress in the fission yeast, and surprisingly, Pap1 regulated genes in S. pombe were distinctly different under nit ROSative stress. Expand
Nitrosative stress induces a novel intra-S checkpoint pathway in Schizosaccharomyces pombe involving phosphorylation of Cdc2 by Wee1.
TLDR
A novel intra-S-phase checkpoint that is activated in S. pombe under nitrosative stress is discovered and it is found that Wee1 phosphorylates Cdc2 Tyr15 which leads to replication slowdown in the fission yeast under nitosative stress. Expand
Gene expression profiling data of Schizosaccharomyces pombe under nitrosative stress using differential display
TLDR
Differential display is used to identify the differentially expressed genes in the fission yeast under nitrosative stress conditions to identify genes which were commonly repressed while several genes were induced upon both 0.1 mM and 1 mM treatments. Expand
Nitric oxide sensing by chlorophyll a.
TLDR
A simple but straightforward way for sensing different NO species using chlorophyll, the source of inspiration being hemoglobin that serves as NO sink in mammalian systems is proposed and the proposed sensing module can be used in microscopic inspection of NO species. Expand
Transcription factors Atf1 and Sty1 promote stress tolerance under nitrosative stress in Schizosaccharomyces pombe.
TLDR
Experimental data obtained in this study reveals a novel role of Atf1 in initiating the replication slowdown in S. pombe under nitrosative stress in a concentration and time dependent manner. Expand
Targeting Histone Chaperone FACT Complex Overcomes 5-Fluorouracil Resistance in Colon Cancer
TLDR
Targeting the FACT complex with curaxins significantly improves the 5-FU efficacy in dMMR colorectal cancer in vitro (∼50-fold decrease in IC50) and in vivo xenograft models. Expand
Myoglobin maturation is driven by the hsp90 chaperone machinery and by soluble guanylyl cyclase
TLDR
It is suggested that hsp90 works in concert with cochaperons and an active sGC‐cGMP signaling pathway to promote heme insertion into immature apo‐Mb, and thus generate functional Mb during muscle myotube formation. Expand
...
1
2
...