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  • Shouming Wang, Nan Chi Wan, +18 authors Peter Charlton
  • Chemistry, Medicine
  • Journal of medicinal chemistry
  • 1 March 2004
  • In our continued effort to identify selective MRP1 modulators, we have developed two novel templates, 3 and 4, through rational drug design by identifying the key pharmacophore interaction at theContinue Reading
  • Prakash Mistry, Adrian J Folkes
  • Chemistry, Medicine
  • Current opinion in investigational drugs
  • 1 November 2002
  • Ontogen is developing ONT-093 (formerly OC-144-093), a P-glycoprotein pump inhibitor, for the potential reversal of multidrug resistance in patients undergoing cancer chemotherapy. The compound isContinue Reading