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Molecular mechanism of anticancer effect of Sclerotium rolfsii lectin in HT29 cells involves differential expression of genes associated with multiple signaling pathways: A microarray analysis.
Sclerotium rolfsii lectin (SRL) is a lectin isolated from fungus S. rolfsii and has high binding specificity toward the oncofetal Thomsen-Friedenreich carbohydrate antigen (Galβ1-3GalNAc-α-O-Ser/Thr,Expand
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A mitogenic lectin from Rhizoctonia bataticola arrests growth, inhibits metastasis, and induces apoptosis in human colon epithelial cancer cells
The correlation between colorectal cancer (CRC) progression and altered expression of N‐glycans can be considered in search for new biomarkers and anticancer agents to control CRC. Earlier N‐glycanExpand
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High mannose N-glycan binding lectin from Remusatia vivipara (RVL) limits cell growth, motility and invasiveness of human breast cancer cells.
Breast cancer known for its high metastatic potential is responsible for large mortality rate amongst women; hence it is imperative to search for effective anti-metastatic molecules despiteExpand
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An L-fucose specific lectin from Aspergillus niger isolated from mycotic keratitis patient and its interaction with human pancreatic adenocarcinoma PANC-1 cells.
An L-fucose specific lectin from pathogenic fungus Aspergillus niger isolated from the corneal smears of keratitis patient was purified in a single step using mucin coupled sepharose-4B column byExpand
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In vitro human gastro-intestinal enzyme digestibility of globulin isolate from oil palm (Elaeis guineensis var. tenera) kernel meal and the bioactivity of the digest
Globulins are the major seed storage proteins (41%) present in oil palm kernel. The study describes the ex vivo digestibility of globulin isolate prepared from oil palm kernel meal. The bioactivityExpand
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Efficacy studies of Sclerotium rolfsii lectin on breast cancer using NOD SCID mouse model
Expression of altered glycans such as TF, Tn, and sTn antigens has been observed in a number of carcinomas which are targeted in cancer therapy. Sclerotium rolfsii lectin (SRL) is known to recognizeExpand
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Purification, characterization and fine sugar specificity of a N-Acetylgalactosamine specific lectin from Adenia hondala
Plant lectins are gaining interest because of their interesting biological properties. Several Adenia species, that are being used in traditional medicine to treat many health ailments have shownExpand
Strategies to Co-express Two Genes Encoding Functionally Related Proteins for Osmolyte Biosynthesis and Ion Homeostasis: Does the Conventional Crossing Method have an Advantage Over the Tissue
Transgenic technology has given a real boost to modern biotechnology by making it possible to transform a plant from susceptible to resistant to many stresses. In order to pyramid genes to improveExpand
A New Framework for Social Media Content Mining and Knowledge Discovery
This paper presents some existing social media content mining techniques and proposed a new approach for efficient Data Mining frame work to extract useful knowledge from the web data. Expand
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