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Cardinal Epigenetic Role of non-coding Regulatory RNAs in Circadian Rhythm
TLDR
The emergence of the earlier unexpected small RNAs is proposed for a historic perspective of epigenetic regulation of the brain clock system.
Pygmy MicroRNA: Surveillance Cops in Therapy Kingdom
TLDR
The current progress of miRNA modulation in the treatment of human diseases to provide an alternative approach to gene therapy is demonstrated and various in vivo delivery strategies are proposed.
Reconstruction and analysis of genome-scale metabolic model of weak Crabtree positive yeast Lachancea kluyveri
TLDR
The genome-scale metabolic construction of L. kluyveri will provide a better understanding of metabolism, particularly that of pyrimidine metabolism and ethyl acetate production, and metabolic flux analysis using the model will enable hypotheses generation to gain a deeperUnderstanding of metabolism in weakly Crabtree positive yeast and in fungal biodiversity in general.
Reconstruction and analysis of genome-scale metabolic model of weak Crabtree positive yeast Lachancea kluyveri
TLDR
The genome-scale metabolic construction of L. kluyveri provides better understanding of metabolism, particularly that of pyrimidine metabolism and ethyl acetate production, as well as enabling it to grow on uracil or urea as the sole nitrogen source.
Non-coding Vibration in Circadian Oscillation
TLDR
The basic role of small regulatory RNA and their epigenetic circuits in brain clock activity are summed up.