Pradeep M Gupte

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In anesthetized patients, acute decreases in cardiac output (CO) are often reflected as decreases in end-tidal CO2 tension (PETCO2), but the quantitative relationship between the changes in CO and the changes in PETCO2 is uncertain. We hypothesize that a quantitative relationship can be demonstrated if timing of the measurements in each episode of(More)
The automated metabolic profile provides the physician with a comprehensive review and graphic display of the patient's nutritional status, energy expenditure, substrate utilization, and nutritional requirements. A paramedical assistant performs all data acquisition, anthropometric and indirect calorimetric measurements. Data reduction is performed on a(More)
In cerebral ischemia, measurement of cerebral blood flow (CBF) alone is not a sensitive or specific predictor of tissue survival. Measurements of oxygen metabolism, which are directly related to cellular energy metabolism, are better predictors of tissue survival and the best of these is the "oxygen extraction fraction" (OEF). Elevation of OEF in Stage 2(More)
A new (17)O-labeled blood contrast agent was injected intravenously in control dogs. Electrocardiogram (ECG)-triggered myocardial T(1)rho imaging was performed to obtain spin-locking T(1)rho-weighted myocardial signals for the detection of resultant metabolite H(2) (17)O water in the heart. Bolus and slow injection methods of various doses of the(More)
A computer program was written to improve quality control and risk management of patients on ventilators. The software was designed to run on the new-generation Spacelabs PC Monitor interfaced to the Puritan-Bennett 7200a ventilator. Before the program allows connection of the ventilator to a patient, the ventilator is polled for initial hardware status,(More)
Clinical monitoring of isolated parameters may lead to erroneous conclusions or conflicting speculations about the patient's general physiological status. Data derived from two or three primary parameters may provide a better understanding of the patient's overall status. Four automated profiles have been designed to aid in the management of critically ill(More)
To evaluate the validity of organ surface oxygen tension monitoring for assessment of cerebral perfusion, the oxygen tension in brain surface (PbsO 2), intracerebral tissue (PicO 2), and conjunctiva (PcjO 2) were measured simultaneously during hypo- and hyperventilation in dogs, and the comparative study was done. p ]PbsO 2 and PicO 2 significantly(More)
A simple means of evaluating the immune function of critically ill patients has been designed. This system uses 22 input data that are derived from an assessment of humoral and cellular immunity and of the various factors known to influence the immune status. The profile allows quantification of the degree of immune depression as well as follow-up of the(More)
This paper presents a program that analyzes data recorded from a Puritan-Bennett 7200a mechanical ventilator. The program generates graphs of major ventilatory parameters, as well as the derivatives of the parameters, such as respiratory rate and minute volume with respect to time. The program also creates a series of reports that summarizes setting(More)
Contrast dilution curves have been utilized for evaluation of hemodynamic function. Noninvasive techniques for this purpose usually have been qualitative, expensive, and cumbersome with minimal applicability to the newborn infant. The technique of roentgen densitometry has been utilized to screen children with heart murmurs. Characteristic curve patterns(More)