Prabha M. R. Adhikari

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OBJECTIVE To assess the effect of yoga on anthropometry, blood pressure, glycemic control, and oxidative stress in type 2 diabetic patients on standard care in comparison with standard care alone. RESEARCH DESIGN AND METHODS The study involved 123 patients stratified according to groups with microvascular complications, macrovascular complications, and(More)
C peptide is an active peptide hormone with potentially important physiological effects. C peptide has the capacity to diminish glomerular hyperfiltration and reduce urinary albumin excretion in both experimental and human type 1 diabetes. The present study is aimed at correlating the serum C peptide level with that of renal clearance, urinary albumin(More)
Peroxisome proliferator-activated receptors (PPARγ), adiponectin (ADIPOQ) and fat mass and obesity-associated gene (FTO) have been reported as a key candidate genes for obesity, type 2 diabetes (T2D) susceptibility and insulin resistance, and we hypothesize that in the background of obesity, the effect of PPARγ2 (rs1801282), ADIPOQ (rs16861194) and FTO(More)
W e appreciate the thoughtful comments by Sperandei (1) on our article (2). Following are the requested clarifications. Sperandei's first question was on how we could use paired t test and the Wilcoxon signed rank test for analyzing unpaired variables between two groups even though these tests are designed for paired variables. We would like to respond that(More)
BACKGROUND AND OBJECTIVES Potassium inwardly rectifying channel, subfamily J, member 11 (KCNJ11) gene have a key role in insulin secretion and is of substantial interest as a candidate gene for type 2 diabetes (T2D). The current work was performed to delineate the genetic influence of KCNJ11 polymorphisms on risk of T2D in South Indian population through(More)
BACKGROUND Micronutrients such as B12 and folic acid deficiencies are found in higher number in HIV-infected patients. OBJECTIVE We conducted a study to examine the effect of Vitamin B12 and folic acid supplementation on neuropsychiatric manifestations, CD4 count, and anthropometric measurements in HIV-positive patients. MATERIALS AND METHODS Three(More)
AIM Several genetic variants for type 2 diabetes (T2D) have been identified through genome wide association studies (GWAS) from Caucasian population; however replication studies were not consistent across various ethnicities. Objective of the current study is to examine the possible correlation of 9 most significant GWAS single nucleotide polymorphisms(More)
BACKGROUND Deficiency of micronutrients is prevalent even before the development of symptoms of HIV disease and is associated with accelerated HIV disease progression. AIMS This study evaluates the prevalence of folate and Vitamin B12 deficiency in HIV-positive patients with or without tuberculosis (TB) and its association with neuropsychiatric symptoms(More)
Brain dominance and handedness have been of great interest to physicians and neurologists from time immemorial. While handedness deals with motor dominance and cerebral hemisphere producing language , brain hemisity deals with learning characteristics and behavioural styles. A Edinburgh handedness inventory (EHI) published in 1971 (1) measures hand(More)
AIMS/INTRODUCTION Diaphragmatic breathing is known to have a beneficial effect on the cardiopulmonary system, and enhances parasympathetic activation. We evaluated the influence of diaphragmatic breathing on time domain measures of heart rate variability in diabetics and healthy subjects. MATERIALS AND METHODS A total of 122 type 2 diabetics and 94(More)