Prabat Ranjan

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Anticancer agents effect tumor cell killing both in vivo and in vitro through the induction of apoptosis. Endonuclease-mediated internucleosomal DNA fragmentation, the most widely used biochemical marker of apoptosis, has been shown to play a central role in apoptosis in many experimental systems. In the present investigation, we report that activation of(More)
Macrophages, treated in vitro with a combination of cisplatin and interferon (IFN)-gamma, have been shown to develop enhanced tumoricidal activity against a number of tumor cell types, through mechanisms which remain largely unknown. In the present study, we have investigated the mechanism involved in the tumor cell cytotoxicity mediated by cisplatin and(More)
UN CO RR E Adhesions of the labia are rare in the adult population with only a few cases described in the English literature. The etiology of labial adhesions probably relates to vaginal inflammation or irritation. Once the superficial epithelium of the labia is denuded subsequent healing leads to fibrous adhesions between the labia. Etiological factors for(More)
Ectopic acromegaly due to growth hormone-releasing hormone secretion by a bronchial carcinoid is rare. We report a case of bronchial carcinoid presenting with acromegaly due to ectopic growth hormone production. The patient was treated successfully with right pneumonectomy.
We investigated whether murine peritoneal macrophages treated with cisplatin or interferon (IFN)-gamma alone, or in combination, could undergo apoptosis, and whether this results either from the cytotoxic effect of the activating agents or indirectly in an autocrine manner by the cytotoxic molecules released by them upon activation. Our data suggest that(More)
BACKGROUND Influenza A (H1N1) hit the headlines in recent times and created mass hysteria and general panic. The high cost and non-availability of diagnostic laboratory tests for swine flu, especially in the developing countries underlines the need of having a cheaper, easily available, yet reasonably accurate screening test. AIMS This study was carried(More)
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