Poonam Kumar

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In the corpulent James C. Russell corpulent (JCR:LA-cp) rat, hyperinsulinemia leads to induction of lipogenic enzymes via enhanced expression of sterol-regulatory-binding protein (SREBP)-1c. This results in increased hepatic lipid production and hypertriglyceridemia. Information regarding down-regulation of SREBP-1c and lipogenic enzymes by dietary fatty(More)
We previously demonstrated increased apolipoprotein B (apoB) mRNA editing, elevated levels of mRNA for the catalytic component of the apoB mRNA editing complex, apobec-1, and increased secretion of the product of the edited mRNA, apoB48, in very low density lipoproteins (VLDL) in primary cultures of Sprague-Dawley rat hepatocytes following insulin(More)
We compared hepatic expression of genes that regulate lipid biosynthesis and metabolic signaling in liver biopsy specimens from women who were undergoing gastric bypass surgery (GBP) for morbid obesity with that in women undergoing ventral hernia repair who had experienced massive weight loss (MWL) after prior GBP. Comprehensive metabolic profiles of(More)
Background Asthma is a serious global health problem. Global prevalence of asthma ranges from 1% to 18% of population in different countries. In India, prevalence of asthma is 3% of the population. Major depressive disorder is the most common mood disorder often found to be higher among people with chronic health conditions like asthma. Presence of(More)
Facial expression recognition has been a highly researched topic in the field of biometrics for decades. It has been used with the intent of both identifying specific individuals, and in understanding human relations and communication. Grouping these expressions into emotions is a subset of this research, which is still new. The focus of this study is to(More)
Methods Evaluated the use of oral or IM low-dose methotrexate vs placebo in steroid-dependent asthma patients using either parallel or crossover design. 100 patients enrolled in study attending the ent and allergy centre (India)panchkula patients were on long term steroid therapy for more than 1 years. Age of patients between 30 to 50 years. Study comparing(More)
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