• Publications
  • Influence
The Simons Genome Diversity Project: 300 genomes from 142 diverse populations
It is demonstrated that indigenous Australians, New Guineans and Andamanese do not derive substantial ancestry from an early dispersal of modern humans; instead, their modern human ancestry is consistent with coming from the same source as that of other non-Africans.
Upper Palaeolithic Siberian genome reveals dual ancestry of Native Americans
The findings reveal that western Eurasian genetic signatures in modern-day Native Americans derive not only from post-Columbian admixture, as commonly thought, but also from a mixed ancestry of the First Americans.
The genetic history of Ice Age Europe
Modern humans arrived in Europe ~45,000 years ago, but little is known about their genetic composition before the start of farming ~8,500 years ago. We analyze genome-wide data from 51 Eurasians from
Genomic Variation in Seven Khoe-San Groups Reveals Adaptation and Complex African History
Genetic variation in various sub-Saharan populations did not localize the origin of modern humans to a single geographic region within Africa; instead, it indicated a history of admixture and stratification, and illustrated the importance of African genomic diversity in understanding human evolutionary history.
The genome of a Late Pleistocene human from a Clovis burial site in western Montana
The genome sequence of a male infant recovered from the Anzick burial site in western Montana is sequenced and it is shown that the gene flow from the Siberian Upper Palaeolithic Mal’ta population into Native American ancestors is also shared by the AnZick-1 individual and thus happened before 12,600 years bp.
Origins and Genetic Legacy of Neolithic Farmers and Hunter-Gatherers in Europe
The results suggest that migration from southern Europe catalyzed the spread of agriculture and that admixture in the wake of this expansion eventually shaped the genomic landscape of modern-day Europe.
An early modern human from Romania with a recent Neanderthal ancestor
DNA from a 37,000–42,000-year-old modern human from Peştera cu Oase, Romania is analysed, finding that on the order of 6–9% of the genome of the Oase individual is derived from Neanderthals, more than any other modern human sequenced to date.
A high-coverage Neandertal genome from Vindija Cave in Croatia
The genome of a female Neandertal from ~50,000 years ago from Vindija Cave, Croatia, is sequenced to ~30-fold genomic coverage, allowing 10 to 20% more Ne andertal DNA to be identified in present-day humans, including variants involved in low-density lipoprotein cholesterol concentrations, schizophrenia, and other diseases.
Genomic Diversity and Admixture Differs for Stone-Age Scandinavian Foragers and Farmers
Hunters and Farmers The Neolithic period in Europe saw the transition from a hunter-gatherer lifestyle to farming. Previous genetic analyses have suggested that hunter-gatherers were replaced by
Separating endogenous ancient DNA from modern day contamination in a Siberian Neandertal
A statistical framework is designed to isolate endogenous ancient DNA sequences from contaminating sequences using postmortem degradation patterns and was able to reduce high-contamination fractions to negligible levels.