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Arginine (Arg) has been used for recognizing negatively charged biological molecules, cell penetration, and oligosaccharide mass signal enhancement. The versatility of Arg has inspired the need to develop Arg analogs and to research the structural effects of incorporating Arg analogs. Accordingly, we investigated the effect of Arg side chain length on helix(More)
The charge-containing hydrophilic functionalities of encoded charged amino acids are linked to the backbone via different numbers of hydrophobic methylenes, despite the apparent electrostatic nature of protein ion pairing interactions. To investigate the effect of side chain length of guanidinium- and carboxylate-containing residues on ion pairing(More)
In this paper, we study a novel paradigm of viral marketing with the goal to sustain the influential effectiveness in the network. We study from real cases such as the Ice Bucket Challenges for the ALS awareness, and figure out the "easy come and easy go" phenomenon in the marketing promotion. Such a natural property is fully unexplored in the literature,(More)
In this paper, we explore a novel framework to generate a well-known text cloud visualiza-tion with the conceptual sense. The traditional text cloud is usually generated according to the word occurrence, possibly including the idf-based concept for word weight. The solution is applicable for the long articles. However, for a set of short sentences such as(More)
β-Sheet is one of the major protein secondary structures. Oppositely charged residues are frequently observed across neighboring strands in antiparallel sheets, suggesting the importance of cross-strand ion pairing interactions. The charged amino acids Asp, Glu, Arg, and Lys have different numbers of hydrophobic methylenes linking the charged functionality(More)
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