Pleuni E Hooijman

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The mechanisms that control cardiac contractility are complex. Recent work we conducted in vertebrate skeletal muscle identified a new state of myosin, the super-relaxed state (SRX), which had a very low metabolic rate. To determine whether this state also exists in cardiac muscle we used quantitative epi-fluorescence to measure single nucleotide turnovers(More)
MASMOUDI et al. [1] reported an exciting pilot study on the beneficial effects of unilateral phrenic nerve stimulation on diaphragm muscle trophicity and structure in mechanically ventilated sheep. They observed that, during 72 h of mechanical ventilation, stimulation sessions of 30 min at 4-h intervals attenuated the development of muscle fibre atrophy in(More)
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