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The expression levels of platelet adhesive receptors in PRP derived platelet concentrates during storage
- Nassaji Fatemeh, Ghasemzadeh Mehran, Pirmohammad Jamaat Zeynab, Hosseini Ehteramolsadat
- 15 April 2016
Significant decreases in the expression of platelet receptors GPIbα and GPVI after 5 days storage are shown, suggesting a major defect in adhesive function of platelets during this term.
THE EXPRESSION LOSS OF GPIBα DUE TO ECTODOMAIN SHEDDING IN PRP DERIVED PLATELET CONCENTRATES DURING STORAGE
Background : Platelet adhesion typically occurs by the critical role of GPIb-V-IX in capturing free-flowing platelets to the injured vessel wall where its rapid binding kinetics enables platelet…