Piotr W. Olejniczak

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OBJECTIVE The long-term efficacy and safety of responsive direct neurostimulation was assessed in adults with medically refractory partial onset seizures. METHODS All participants were treated with a cranially implanted responsive neurostimulator that delivers stimulation to 1 or 2 seizure foci via chronically implanted electrodes when specific(More)
PURPOSE To assess the effect of vagus nerve stimulation (VNS) on interictal epileptiform activity in the human hippocampus. Clinical studies have established the efficacy of vagus nerve stimulation in patients with epilepsy (VNS Study Group, 1995), although the electrophysiologic effects of VNS on the human hippocampus and mesial temporal lobe structures(More)
SUMMARY This review article introduces the reader to the very basics of electroencephalography (EEG). It tries to explain in simple terms the physiologic principles of EEG generation and organization at the cellular, cortical and subcortical levels. It also introduces the basic EEG terminology (see the key words).
The first comprehensive epilepsy surgery center in Louisiana was established in 1990 at the Louisiana State University Medical Center in New Orleans by the Departments of Neurology and Neurosurgery. The center performs a wide variety of diagnostic tests essential for the medical and surgical treatment of epilepsy including EEG and video monitoring,(More)
Postictal EEG suppression and slowing recorded with scalp electrodes in patients with partial epilepsy is often maximal over the cortical area of ictal onset. The aim of this study was to determine whether a quantitative relationship exists between immediate postictal EEG suppression and hippocampal atrophy. Immediate postictal EEG was analyzed in 31(More)
PURPOSE Epilepsy research has identified higher rates of learning disorders in patients with temporal lobe epilepsy (TLE). However, most studies have not adequately assessed complex functional adult learning skills, such as reading comprehension and written language. We designed this study to evaluate our predictions that higher rates of reading(More)
Burst suppression (BS) consists of bursts of high-voltage slow and sharp wave activity alternating with periods of background suppression in the electroencephalogram (EEG). When induced by deep anesthesia or encephalopathy, BS is bihemispheric and is often viewed as a non-epileptic phenomenon. In contrast, unihemispheric BS is rare and its clinical(More)
The clinical diagnosis of Creutzfeldt-Jakob disease (CJD) is largely based on the 1998 World Health Organization diagnostic criteria. Unfortunately, rigid compliance with these criteria may result in failure to recognize sporadic CJD (sCJD), especially early in its course when focal findings predominate and traditional red flags are not yet present. A(More)
OBJECTIVE Evaluate the seizure-reduction response and safety of brain-responsive stimulation in adults with medically intractable partial-onset seizures of neocortical origin. METHODS Patients with partial seizures of neocortical origin were identified from prospective clinical trials of a brain-responsive neurostimulator (RNS System, NeuroPace). The(More)
Drug-induced burst suppression (DIBS) is bihemispheric and bisymmetric in adults and older children. However, asymmetric DIBS may occur if a pathological process is affecting one hemisphere only or both hemispheres disproportionately. The usual suspect is a destructive lesion; an irritative or epileptogenic lesion is usually not invoked to explain DIBS(More)