Piotr Banski

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The physiological state of eukaryotic cells controls nuclear trafficking of numerous cargos. For example, stress results in the inhibition of classical protein import, which is characterized by the redistribution of several transport factors. As such, importin-α and cellular apoptosis susceptibility protein (CAS) accumulate in nuclei of heat-shocked cells;(More)
The nucleolus has emerged as a key player that regulates cell growth, survival and the recovery from stress. Progress in proteomics made it possible to sequence the nucleolar proteome under different physiological conditions. Together with other research, this work revealed the presence of multiple chaperones and co-chaperones in the nucleolus. Molecular(More)
Hsc70s are constitutively synthesized members of the 70-kDa chaperone family; they are essential for viability and conserved among all organisms. When eukaryotic cells recover from stress, hsc70s accumulate in nucleoli by an unknown mechanism. Our studies were undertaken to characterize the signaling events and the targeting sequence required to concentrate(More)
ERK and Akt kinases are key components that participate in numerous regulatory processes, including the response to stress. Using novel tools for quantitative immunofluorescence, we show that oxidant exposure controls the intracellular activation and localization of ERK1/2 and Akt. Oxidative stress alters the nuclear/cytoplasmic levels of the kinases,(More)
Nucleoli are composed of possibly several thousand different proteins and represent the most conspicuous compartments in the nucleus; they play a crucial role in the proper execution of many cellular processes. As such, nucleoli carry out ribosome biogenesis and sequester or associate with key molecules that regulate cell cycle progression, tumorigenesis,(More)
We present the annotation architecture of the National Corpus of Polish and discuss problems identified in the TEI stand-off annotation system, which, in its current version, is still very much unfinished and untested, due to both technical reasons (lack of tools implementing the TEIdefined XPointer schemes) and certain problems concerning data(More)
Nuclear pore complexes (NPCs) provide the only sites for macromolecular transport between nucleus and cytoplasm. The nucleoporin p62, a component of higher eukaryotic NPCs, is located at the central gated channel and involved in nuclear trafficking of various cargos. p62 is organized into an N-terminal segment that contains FXFG repeats and binds the(More)
This paper documents a pilot study conducted as part of the development of a new corpus processing system at the Institut für Deutsche Sprache in Mannheim and in the context of the ISO TC37 SC4/WG6 activity on the suggested work item proposal “Corpus Query Lingua Franca”. We describe the first phase of our research: the initial formulation of functionality(More)
This article describes POLIQARP, a corpus indexing and query tool, which understands positional tagsets and which does not assume that word forms are annotated with unique morphosyntactic tags. POLIQARP is designed to be applicable to a variety of languages and tagsets: it works with XML-encoded texts, uses the UTF-8 character set, and allows for an(More)