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STUDY TYPE Therapy (meta-analysis) Level of Evidence 1a. OBJECTIVES To assess the effectiveness and complications of transobturator tape (inside-out and outside-in, TOT) by means of a systematic review of direct and indirect randomized controlled trials (RCTs). METHOD MEDLINE, EMBASE, CINAHL, LILIACS (up to December 2008), CENTRAL (The Cochrane Library,(More)
The anti-VEGF receptor 2 antibody IMC-1121B is a promising antiangiogenic drug being tested for treatment of breast and gastric cancer. We have determined the structure of the 1121B Fab fragment in complex with domain 3 of VEGFR2, as well as the structure of a different neutralizing anti-VEGFR2 antibody, 6.64, also in complex with VEGFR2 domain 3. The two(More)
The objective of the study was to determine the prevalence of domestic violence (DV) in women attending an antenatal clinic in a Delhi hospital; to investigate any associated risk factors; main perpetrators; forms and severity of violence. An anonymous validated questionnaire was used. A total of 26.9% of women reported physical abuse. Emotional and sexual(More)
Background: Childhood apraxia of speech (CAS) is a neurological childhood speech disorder in which the precision and consistency of movements underlying speech are impaired in the absence of neuromuscular deficits. CAS is a controversial disorder in terms of diagnosis and intervention approaches. Purpose: Due to heterogeneity of children with CAS, a speech(More)
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