Ubiquitin-protein ligases (E3s) regulate diverse cellular processes by mediating protein ubiquitination. The c-Cbl proto-oncogene is a RING family E3 that recognizes activated receptor tyrosine… (More)
A “botnet” consists of a network of compromised computers controlled by an attacker (“botmaster”). Recently, botnets have become the root cause of many Internet attacks.… (More)
The intracellular mechanism(s) by which a cell determines the duration of extracellular signal–regulated kinase (ERK) activation is not well understood. We have investigated the role of STEP, a… (More)
An information technology (IT) fashion is a transitory collective belief that an IT is new, efficient, and at the forefront of practice. I find that following IT fashions can legitimize organizations… (More)
The quantitative study of the cell growth has led to many fundamental insights in our understanding of a wide range of subjects, from the cell cycle to senescence. Of particular importance is the… (More)
Cryptococcus neoformans is a human-pathogenic fungus that has evolved into three distinct varieties that infect most prominently the central nervous system. A sexual cycle involving haploid cells of… (More)
In this demo, we present the Microsoft Complex Event Processing (CEP) Server, Microsoft CEP for short. Microsoft CEP is an event stream processing system featured by its declarative query language… (More)
Discriminative dictionary learning aims to learn a dictionary from training samples to enhance the discriminative capability of their coding vectors. Several discrimination terms have been proposed… (More)
Spatial genome organization and its effect on transcription remains a fundamental question. We applied an advanced chromatin interaction analysis by paired-end tag sequencing (ChIA-PET) strategy to… (More)
Appropriate application of service selection based on QoS-aware can bring great benefits to service consumers, as it is able to reduce redundancy in search. It also generates advantages for service… (More)