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A leading edge 90 nm technology with 1.2 nm physical gate oxide, 50 nm gate length, strained silicon, NiSi, 7 layers of Cu interconnects, and low k CDO for high performance dense logic is presented. Strained silicon is used to increase saturated NMOS and PMOS drive currents by 10-20% and mobility by > 50%. Aggressive design rules and unlanded contacts offer(More)
Herpes simplex virus 1 (HSV-1) is a double-stranded DNA virus that replicates in the nucleus of its human host cell and is known to interact with many cellular DNA repair proteins. In this study, we examined the role of cellular mismatch repair (MMR) proteins in the virus life cycle. Both MSH2 and MLH1 are required for efficient replication of HSV-1 in(More)
The herpes simplex virus type 1 (HSV-1) alkaline nuclease, encoded by the UL12 gene, plays an important role in HSV-1 replication, as a UL12 null mutant displays a severe growth defect. The HSV-1 alkaline exonuclease UL12 interacts with the viral single-stranded DNA binding protein ICP8 and promotes strand exchange in vitro in conjunction with ICP8. We(More)
This article presents a novel evaluation system along with methods to evaluate bilateral coordination of arm function on activities of daily living tasks before and after robot-assisted therapy. An affordable bilateral assessment system (BiAS) consisting of two mini-passive measuring units modeled as three degree of freedom robots is described. The process(More)
Using human papillomavirus (HPV) testing for cervical cancer screening in lower-resource settings (LRS) will result in a significant number of screen-positive women. This analysis compares different triage strategies for detecting cervical precancer and cancer among HPV-positive women in LRS. This was a population-based study of women aged 25-65 years(More)
BACKGROUND An adult zebrafish heart possesses a high capacity of regeneration. However, it has been unclear whether and how myocyte hyperplasia contributes to cardiac remodeling in response to biomechanical stress and whether myocyte hypertrophy exists in the zebrafish. To address these questions, we characterized the zebrafish mutant tr265/tr265, whose(More)
Quantum tunneling between two plasmonic resonators links nonlinear quantum optics with terahertz nanoelectronics. We describe the direct observation of and control over quantum plasmon resonances at length scales in the range 0.4 to 1.3 nanometers across molecular tunnel junctions made of two plasmonic resonators bridged by self-assembled monolayers (SAMs).(More)
It is a very important task that how to classify Web pages automatically and effectively in accordance with the given model for machine learning. The traditional operation modes, including artificial way and semiautomatic way, form category abstracts after domain experts’ personnel inspection and then put the results into a particular class library(More)
The single-system approach is no longer sufficient to handle the load on popular Internet servers, especially for those offering extensive multimedia content. Such services have to be replicated to enhance their availability, performance, and reliability. In a highly replicated and available environment, server selection is an important issue. In this(More)