Piet Borgdorff

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AIM Increased cardiovascular risk after use of selective or nonselective cyclooxygenase-2 (COX-2)-inhibitors might partly be caused by enhanced platelet aggregability. However, an effect of COX-2 inhibition on platelets has so far not been observed in humans. METHODS We tested in healthy volunteers the effect of COX-2-inhibition nearly in-vivo, i.e.(More)
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