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- Robert J Harvey, Ulrike B. Depner, +14 authors Ulrike Müller
- Science
- 2004
Prostaglandin E2 (PGE2) is a crucial mediator of inflammatory pain sensitization. Here, we demonstrate that inhibition of a specific glycine receptor subtype (GlyR alpha3) by PGE2-induced receptor… (More)
- Pierrick Poisbeau, Michael C. Cheney, Michael D. Browning, István Módy
- The Journal of neuroscience : the official…
- 1999
Several protein kinases are known to phosphorylate Ser/Thr residues of certain GABAA receptor subunits. Yet, the effect of phosphorylation on GABAA receptor function in neurons remains controversial,… (More)
- Anne Florence Keller, Jeffrey A. M. Coull, Nadège Chéry, Pierrick Poisbeau, Yves de Koninck
- The Journal of neuroscience : the official…
- 2001
The spinal dorsal horn is the first level of the CNS in which nociceptive input from sensory afferents is integrated and transmitted. Although inhibitory control in this region has a crucial impact… (More)
Silent GABAA synapses during flurazepam withdrawal are region-specific in the hippocampal formation.
- Pierrick Poisbeau, Stephen C. R. Williams, István Módy
- The Journal of neuroscience : the official…
- 1997
Whole-cell patch-clamp recordings were made from CA1 pyramidal and dentate gyrus granule cells (GCs) in hippocampal slices to assess the effects of withdrawal from chronic flurazepam (FRZ) treatment… (More)
- Rémy Schlichter, V K Rybalćhenko, Pierrick Poisbeau, Marc Verleye, Jean Marie Gillardin
- Neuropharmacology
- 2000
We have investigated the effects of 2-ethylamino-6-chloro-4-methyl-4-phenyl-4H-3,1-benzoxazine hydrochloride (etifoxine) on GABA(A) receptor function. Etifoxine displaced [(35)S]TBPS… (More)
- Pierrick Poisbeau, P. Feltz, Rémy Schlichter
- The Journal of physiology
- 1997
1. We have used the whole-cell configuration of the patch-clamp technique to investigate the effects of neuroactive steroids on GABAA receptor-mediated synaptic transmission between rat hypothalamic… (More)
- Maya Aouad, Alexandre Charlet, J. -L. Rodeau, Pierrick Poisbeau
- PAIN®
- 2009
The central processing of peripheral nociceptive messages is highly controlled by the activity of local inhibitory networks in the spinal cord and supraspinal centers. Recently, it has been shown… (More)
- Malika Benbouzid, Viviane Pallage, +5 authors Michel Barrot
- European journal of pain
- 2008
Because of its severity, chronicity, resistance to usual therapy and its consequences on quality of life, neuropathic pain represents a real clinical challenge. Fundamental research on this pathology… (More)
- Alexis Laux, Arnaud H. Muller, +9 authors Yannick Goumon
- The Journal of comparative neurology
- 2011
Endogenous morphine, morphine-6-glucuronide, and codeine, which are structurally identical to vegetal alkaloids, can be synthesized by mammalian cells from dopamine. However, the role of brain… (More)
- Jean Didier Breton, Pierre Veinante, +4 authors Pierrick Poisbeau
- Molecular pain
- 2008
BACKGROUND
Recent evidence suggests that oxytocin (OT), secreted in the superficial spinal cord dorsal horn by descending axons of paraventricular hypothalamic nucleus (PVN) neurons, produces… (More)