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BACKGROUND Conflicting blood pressure-lowering effects of catheter-based renal artery denervation have been reported in patients with resistant hypertension. We compared the ambulatory blood pressure-lowering efficacy and safety of radiofrequency-based renal denervation added to a standardised stepped-care antihypertensive treatment (SSAHT) with the same(More)
Right ventricle ejection fraction (RVEF) evaluated with magnetic resonance imaging is a strong determinant of patient outcomes in pulmonary arterial hypertension. We evaluated the prognostic value of RVEF assessed with conventional planar equilibrium radionuclide angiography at baseline and change 3-6 months after initiating pulmonary arterial(More)
Utility of Doppler echocardiography and tissue Doppler imaging in the estimation of diastolic function in heart failure with normal ejection fraction: a comparative Doppler-conductance catheterization study. Diagnosis of heart failure with preserved ejection fraction: which parameters and diagnostic strategies are more valuable? et al. The patho-physiology(More)
R wave in aVL lead (RaVL) is an old ECG index of left ven-tricular hypertrophy (LVH) described in 1949 by Sokolow and Lyon. 1 During the last decades Sokolow-Lyon index and Cornell voltage or product have been extensively used to detect LVH. 2–5 These 2 latter indexes turned out to have a better diagnostic value but had also some drawbacks such as a(More)
Tissue renin-angiotensin-aldosterone system (RAAS) has attracted much attention because of its physiological and pharmacological implications; however, a clear definition of tissue RAAS is still missing. We aimed to establish a preliminary atlas for the organization of RAAS across 23 different normal human tissues. A set of 37 genes encoding classical and(More)
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