Pierre Toulouse

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The facilitation of the tendon reflex of quadriceps, induced by voluntary contraction of a muscle group in the upper limb, evolves in the three phases and depends on several factos. These include the strength and type (ballistic or ramp) of the contraction. In the absence of any electromyographic activity in the conditioning muscle (from a lesion of its(More)
OBJECT The authors present the use of cortical sulci, segmented from magnetic resonance (MR) imaging, and functional data from functional (f)MR imaging and magnetoencephalography (MEG) in the image-guided surgical management of lesions adjacent to the sensorimotor cortex. METHODS In an initial set of 11 patients, sulci near lesions were automatically(More)
OBJECTIVE Our main goal was to evaluate the accuracy of an original non-supervised spatio-temporal magnetoencephalography (MEG) localization method used to characterize interictal spikes generators. METHODS MEG and stereotactic intracerebral recordings (stereo-electro-encephalographic exploration, SEEG) data were analyzed independently in 4 patients. MEG(More)
To analyze the factors that influence the conditioning of monosynaptic reflexes by the Jendrassik maneuver, the latter was replaced by a rapid, isolated, reproducible contraction of the wrist extensors; this procedure facilitated reflexes as effectively as the classical Jendrassik maneuver. The results were expressed quantitatively in relation to maximal(More)
It is nowadays well known that there are reflex loops starting in the spinal cord, relaying in various supraspinal structures and descending back to the cord. These long-loops regulate motor responses and work in cooperation with segmental mono- and polysynaptic reflexes. The role of certain well-documented long-loop reflexes is reviewed. The existence of(More)
Within the scope of three-dimensional brain imaging we propose an inter-individual fusion scheme to register functional activations relatively to anatomical cortical structures, the sulci. This approach is local and non-linear. It relies on a statistical sulci shape model accounting for the inter-individual variability of a population of subjects, and(More)
This study compares the facilitation of various lower limb reflex arcs brought about by a selective contraction of a well-defined upper limb muscle group in able-bodied healthy subjects. Quantitatively (results expressed as a percentage of maximal motor response), the quadriceps tendon reflex is facilitated more than the soleus and biceps femoris tendon(More)
The results of the application of classification methods to electromyograph signals of weak contractions in normal and myopathic subjects are described. Methods of pattern recognition, previously presented, allow the selection of representative motor unit action potentials. The analysis is done with ordinal qualitative variables obtained by identification(More)
Recovery after stroke is closely linked to cerebral plasticity. Magnetoencephalography (MEG) is a non-invasive technique, which allows location of cerebral cells activities. In the present work, a cohort of patients has been studied with MEG. Twelve patients with a recent ischemic or hemorragic stroke were included as soon as possible after onset of stroke.(More)
A new automatic EMG analysis and on-line assignment of MUAP into 8 dynamic cluster algorithm classes (P1......P8) were applied to female relatives of patients with Duchenne type dystrophy. Promising results are given. MUAP amplitude and duration differed significantly in the female relatives compared to the control subjects. MUAP distribution patterns found(More)