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STUDY DESIGN Review article on bone metabolism and therapeutic approach on bone loss in patients with spinal cord injury (SCI). OBJECTIVE The first part aims to describe the process of bone demineralization and its effects on bone mass in patients with SCI. The second part describes and discusses the therapeutic approaches to limiting the alteration in(More)
Compression was applied to the distal femoral growth plate in rabbits. Measurements of bone length and microscopic studies of the physis showed that the axial growth rate decreased proportionally with the compression force; forces greater than 30 N caused cartilage cell damage and rapid cessation of physeal growth.
The use of general descriptive names, registered names, trademarks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. Product liability: The publishers cannot guarantee the accuracy of any information about the(More)
The aim of this study was to define precisely the imaging of the canals of the temporal bone by means of high-resolution computed tomography (HR CT). Based on 24 temporal bones removed from embalmed cadavers and investigated with HR CT, several canals were studied: the canal of the chorda tympani (CdT), the canal of the auricular branch of the vagus nerve(More)
BACKGROUND Laparoscopic exposure of pelvic nerves has opened a new area in the field of neuromodulation. However, electrode design and material deterioration remain issues that limit clinical application. The objective of this study was to evaluate experimentally the laparoscopic implantation of different types of neural electrodes in order to achieve(More)
We present the results of a 5-year patient follow-up after implantation of an original neuroprosthesis. The system is able to stimulate both epimysial and neural electrodes in such a way that the complete flexor-extensor chain of the lower limb can be activated without using the withdrawal reflex. We demonstrate that standing and assisted walking are(More)
Paraplegia means a live long sentence of sensory loss, paralysis and dependence with approximately 1000 new victims in every European country every year and 11.500 new traumatic SCI cases in the US. respectively. Sixty percent are injured before age 30. More than 90% of SCI victims may survive with nearly normal experience of live. Most patients will(More)
Our main objective is to demonstrate the feasibility of a cortical neuroprosthesis, interfaced with the visual cortex, as a means through which a limited but useful visual sense may be restored to profoundly blind people. Although there are still a number of important unanswered questions and many problems have to be solved before a Cortical Visual(More)