Pierre R. Fournie

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PURPOSE We compared an iontophoresis riboflavin delivery technique for transepithelial corneal collagen crosslinking (I-CXL) with a conventional CXL (C-CXL). METHODS We designed three experimental sets using 152 New Zealand rabbits to study riboflavin application by iontophoresis using charged riboflavin solution (Ricrolin+) with a 1-mA current for 5(More)
PURPOSE To report the use of Descemet stripping automated endothelial keratoplasty (DSAEK) and to treat visual loss in Descemet membrane (DM) breaks after forceps delivery. METHODS An 8-year-old boy presented with unilateral DM ruptures secondary to forceps delivery. Central, vertically oriented DM breaks significantly decreased visual acuity.(More)
Once a corneal scar develops, surgical management remains the only option for visual rehabilitation. Corneal transplantation is the definitive treatment for a corneal scar. In addition to the challenges posed by graft rejections and other postoperative complications, the lack of high-quality donor corneas can limit the benefits possible with keratoplasty.(More)
PURPOSE To report refractive, topographic, and biomechanical outcomes, efficiency, and safety of corneal collagen crosslinking (CXL) 1, 3, 6, and 12 months after treatment. SETTING National Reference Centre for Keratoconus, Bordeaux and Toulouse, France. DESIGN Case series. METHODS This retrospective uncontrolled double-center study comprised eyes(More)
OBJECTIVE To compare refractive performance and safety of laser in situ keratomileusis (LASIK) and Artisan phakic intraocular lens (PIOL) for moderately high myopia. DESIGN A prospective, randomized trial with paired eye control. PARTICIPANTS Twenty-five patients with myopia ranging from -8.00 to -12.00 diopters (D). INTERVENTION For each patient, one(More)
PURPOSE To characterize the expression of the bone morphogenetic protein-1 (BMP-1)/tolloid-like proteinases (collectively called BTPs), which include BMP-1, mammalian tolloid (mTLD), and mammalian tolloid-like 1 (mTLL-1) and 2 (mTLL-2), as well as the associated proteins procollagen C-proteinase enhancers (PCPE-1 and -2), in corneal scarring. METHODS(More)
INTRODUCTION The aim of the present study was to evaluate the clinical usefulness of riboflavin- and ultraviolet-A (UV-A)-induced collagen cross-linking (CXL) on progressive keratoconus. PATIENTS AND METHODS Twenty eyes of 20 patients with progressive keratoconus were included in a prospective, nonrandomized pilot study. The preoperative progression of(More)
OBJECTIVE To alert ophthalmologists of the possibility of an aggravation of forme fruste keratoconus after photorefractive keratectomy (PRK). DESIGN Clinical case report. INTERVENTION Standard bilateral PRK for low myopia. MAIN OUTCOME MEASURES Corneal topography, corneal thickness, and visual acuity. RESULTS Corneal ectasia occurred bilaterally(More)
PURPOSE To compare refractive performance of Artisan (Ophtec, Groningen, The Netherlands) or Verisyse phakic intraocular lens and its foldable version, Artiflex (Ophtec), for the correction of moderately high myopia. DESIGN Randomized pilot study. METHODS setting: Institutional practice. patient population: Thirty-one patients with myopia that ranged(More)
A 78-year-old man who had had uneventful extracapsular cataract extraction in the left eye 3 months earlier developed pyoderma gangrenosum (PG)-associated peripheral ulcerative keratitis (PUK) after suture removal. The patient had a 13-year history of PG associated with monoclonal immunoglobulin-A gammopathy. He presented with extensive, painful PUK at the(More)