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PURPOSE To report the use of Descemet stripping automated endothelial keratoplasty (DSAEK) and to treat visual loss in Descemet membrane (DM) breaks after forceps delivery. METHODS An 8-year-old boy presented with unilateral DM ruptures secondary to forceps delivery. Central, vertically oriented DM breaks significantly decreased visual acuity.(More)
PURPOSE We compared an iontophoresis riboflavin delivery technique for transepithelial corneal collagen crosslinking (I-CXL) with a conventional CXL (C-CXL). METHODS We designed three experimental sets using 152 New Zealand rabbits to study riboflavin application by iontophoresis using charged riboflavin solution (Ricrolin+) with a 1-mA current for 5(More)
PURPOSE To investigate type XII collagen expression in corneal scars in vivo. METHODS Type XII collagen protein expression was evaluated by immunohistochemistry in human corneal scars and in a mouse model of corneal scarring at several time points (from day 7 to day 210) after full-thickness excision. Alternative splice variants of the NC3 and NC1 domains(More)
OBJECTIVE To alert ophthalmologists of the possibility of an aggravation of forme fruste keratoconus after photorefractive keratectomy (PRK). DESIGN Clinical case report. INTERVENTION Standard bilateral PRK for low myopia. MAIN OUTCOME MEASURES Corneal topography, corneal thickness, and visual acuity. RESULTS Corneal ectasia occurred bilaterally(More)
OBJECTIVE To further investigate the hypothesis that epithelial ingrowth in human corneas after laser-assisted in situ keratomileusis (LASIK) correlates with basement membrane remodeling, as suggested by the presence of matrix metalloproteinase 9 around epithelial cells in the lamellar scar. METHODS Immunohistochemical analysis and transmission electron(More)
OBJECTIVE To compare refractive performance and safety of laser in situ keratomileusis (LASIK) and Artisan phakic intraocular lens (PIOL) for moderately high myopia. DESIGN A prospective, randomized trial with paired eye control. PARTICIPANTS Twenty-five patients with myopia ranging from -8.00 to -12.00 diopters (D). INTERVENTION For each patient, one(More)
PURPOSE To compare refractive performance of Artisan (Ophtec, Groningen, The Netherlands) or Verisyse phakic intraocular lens and its foldable version, Artiflex (Ophtec), for the correction of moderately high myopia. DESIGN Randomized pilot study. METHODS setting: Institutional practice. patient population: Thirty-one patients with myopia that ranged(More)
PURPOSE To report refractive, topographic, and biomechanical outcomes, efficiency, and safety of corneal collagen crosslinking (CXL) 1, 3, 6, and 12 months after treatment. SETTING National Reference Centre for Keratoconus, Bordeaux and Toulouse, France. DESIGN Case series. METHODS This retrospective uncontrolled double-center study comprised eyes(More)
Once a corneal scar develops, surgical management remains the only option for visual rehabilitation. Corneal transplantation is the definitive treatment for a corneal scar. In addition to the challenges posed by graft rejections and other postoperative complications, the lack of high-quality donor corneas can limit the benefits possible with keratoplasty.(More)
OBJECTIVE To define predictive factors after manual implantation of intrastromal corneal ring segments (Ferrara ring) for the management of keratoconus. PATIENTS AND METHODS Twenty-five eyes of 25 patients with keratoconus were implanted with Ferrara intracorneal ring segments using a mechanical procedure. We measured corneal ring implantation depth, best(More)