Pierre Mahou

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We present a method to label and trace the lineage of multiple neural progenitors simultaneously in vertebrate animals via multiaddressable genome-integrative color (MAGIC) markers. We achieve permanent expression of combinatorial labels from new Brainbow transgenes introduced in embryonic neural progenitors with electroporation of transposon vectors. In(More)
We study both experimentally and theoretically the generation of photon pairs by spontaneous four-wave mixing (SFWM) in standard birefringent optical fibers. The ability to produce a range of two-photon spectral states, from highly correlated (entangled) to completely factorable, by means of cross-polarized birefringent phase matching, is explored. A simple(More)
We achieve simultaneous two-photon excitation of three chromophores with distinct absorption spectra using synchronized pulses from a femtosecond laser and an optical parametric oscillator. The two beams generate separate multiphoton processes, and their spatiotemporal overlap provides an additional two-photon excitation route, with submicrometer overlay of(More)
To the Editor: Several studies recently demonstrated that one-photon (1P) light-sheet imaging gives access to the spontaneous activity of a large fraction of the zebrafish larval brain at nearly single-cell resolution1–3. This imaging method, however, requires an intense and extended illumination at a wavelength (l = 488 nm) that lies within the most(More)
TCGA-Assembler is fully compatible with Firehose and can directly process data files downloaded from Firehose. TCGA-Assembler will remain freely available and open source. In the future, more dataprocessing and analysis functions will be continuously added to TCGA-Assembler on the basis of user feedback and new research needs. We expect that TCGA-Assembler(More)
Nonlinear microscopy can be used to probe the intrinsic optical properties of biological tissues. Using femtosecond pulses, third-harmonic generation (THG) and four-wave mixing (FWM) signals can be efficiently produced and detected simultaneously. Both signals probe a similar parameter, i.e. the real part of the third-order nonlinear susceptibility χ((3)).(More)
We study theoretically and numerically third-harmonic generation (THG) from model geometries (interfaces, slabs, periodic media) illuminated by Bessel beams produced by focusing an annular intensity profile. Bessel beams exhibit a phase and intensity distribution near focus different from Gaussian beams, resulting in distinct THG phase matching properties(More)
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